SILA-123

CAT: 0931-T200498-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0931-T200498-01Size:25 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

2911585-37-8

Target

Apoptosis, FLT

Related Pathways

Angiogenesis, Tyrosine Kinase/Adaptors, Apoptosis

Bioactivity

SILA-123, an inhibitor of FLT3 (FLT3-WT: IC50=2.1 nM; FLT3-ITD: IC50=1.0 nM), induces cell apoptosis by hindering the cell cycle progression at the G0/G1 phase through the suppression of FLT3 phosphorylation and its downstream signaling pathways. This compound is utilized in the study of acute myeloid leukemia.

Smiles

O=C(NC=1C=CC(=CC1)C=2C=C(N=C3ON=C(N)C32)C)NC4=CC=C(C=C4)C(C)(C)C

Molecular Formula

C24H25N5O2

Molecular Weight

415.49

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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Alternative Products

Catalog	Name
HY-162936	SILA-123
461841-01	P-Fluorohexahydro-sila-difenidol
sc-484525	Methyl Vinyl[1]sila Ferrocenophane
sc-257953	P-Fluorohexahydro-sila-difenidol hydrochloride
4TI-0665-41	Automated Roll Heat Sealer SiLA Driver
HY-P11354	THR-123
HY-12378-01	BQ-123
MBS3612332-01	Rhodamine 123
S-3665-MTBE	123-Trichloropropane
110079	Hsp-123

SILA-123

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