STAT3-IN-35

• Target:

  STAT

• Related Pathways:

  Stem Cells|||JAK/STAT signaling

• Bioactivity:

  STAT3-IN-35 is a STAT3 inhibitor that binds to the SH2 domain. This compound inhibits the phosphorylation of STAT3 and exhibits antiproliferative activity in triple-negative breast cancer (TNBC) cell lines. Additionally, STAT3-IN-35 has demonstrated toxicity and potent antitumor activity in TNBC xenograft models.

• Smiles:

  O=C1C2=C(C=3C(C1=O)=CC=CC3)OC4=C2CCN([C@@H](CC(C)C)CO)C4

• Molecular Formula:

  C21H23NO4

• Molecular Weight:

  353.41

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2849535-96-0