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NLRP3-IN-45

CAT: 0931-T200214-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T200214-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
NOD-like Receptor (NLR)
Related Pathways
Immunology/Inflammation
Bioactivity
NLRP3-IN-45 (D6) serves as an inhibitor specifically targeting the NLRP3 inflammasome, demonstrated through its ability to curb the activity of IL-1β (IC 50 = 41.79 nM) . It effectively prevents the activation of the NLRP3 inflammasome while sparing the initial stages of its activation process. Furthermore, NLRP3-IN-45 has been shown to selectively inhibit NLRP3 inflammasome activation in the LPS-induced acute lung injury (ALI) mouse model.
Molecular Formula
C27H30FNO6
Molecular Weight
483.53
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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