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Recombinant mouse TIMP-1 protein

CAT: 0112-ATGP4040-050Size: 50 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP4040-050Size:50 µg
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Description
TIMP-1, also known as metalloproteinase inhibitor 1, is a member of the TIMP family. Tissue inhibitors of metalloproteinases (TIMP) family are natural inhibitors of the matrix metalloproteinases (MMPs), the zinc enzymes involved in extracellular matrix maintenance and remodeling. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. It has been identified as a multifunctional molecule with divergent functions. Recombinant Mouse TIMP-1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Name Alternative
Timp1, Cl, Clgi, EPA, Timp, TIMP-1, TPA-S1, Metalloproteinase inhibitor 1, Collagenase inhibitor 16C8 fibroblast, Erythroid-potentiating activity, TPA-induced protein
Expression System
Baculovirus
Antigen Species
Mouse
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 95% by SDS-PAGE
Molecular Weight
21kDa (187aa)
Additionnal Information
ATGP4040-10 µg, ATGP4040-20 µg, ATGP4040-50 µg, ATGP4040-100 µg, ATGP4040-250 µg, ATGP4040-500 µg, ATGP4040-1 mg, ATGP4040-10, ATGP4040-20, ATGP4040-50, ATGP4040-100, ATGP4040-250, ATGP4040-500, ATGP4040-1
References & Citations
M Toricelli, et al. (2013) Molecular Cancer 12:1095.; ; Gardner., et al. (2003) J. Neurosci. Res. 74:801-806.; ; Osthues A., et al. (1992) FEBS. Lett. 296:16-20.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) 10% glycerol
Scientific Category
Angiogenesis, Cardiovascular, Adhesion & Movement
NCBI Accession Number
NP_035723.2
Uniprot Accession Number
P12032
Species
Mouse
N Terminal Sequence
Cys25

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