Recombinant human Complement Factor B protein

CAT: 0112-ATGP3903-020Size: 20 µgDry Ice: NoHazardous: No
CAT#:0112-ATGP3903-020Size:20 µg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
Complement factor B, also known as CFB, is a component of the alternative pathway of complement activation.Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, itis cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The activesubunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb isinvolved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. Recombinant human Complement factor B protein, fused to His-tag at C-terminus, was expressed in insect cell and purified byusing conventional chromatography techniques.
Product Name Alternative
CFB, C3/C5 convertase, Glycine-rich beta glycoprotein, GBG, PBF2, Properdin factor B, BF, BFD, AHUS4, ARMD14, CFAB, CFBD, FB, FBI12, GBG, H2-Bf
Expression System
Baculovirus
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 90% by SDS-PAGE
Molecular Weight
58.1 kDa (514aa)
Additionnal Information
Complement Factor B, ATGP3903-10 µg, ATGP3903-20 µg, ATGP3903-50 µg, ATGP3903-100 µg, ATGP3903-250 µg, ATGP3903-500 µg, ATGP3903-1 mg, ATGP3903-10, ATGP3903-20, ATGP3903-50, ATGP3903-100, ATGP3903-250, ATGP3903-500, ATGP3903-1
References & Citations
Francis PJ., et al. (2009) J Med Genet. 46:300-307.; ; Schwaeble W., et al (1993) . Immunobiology 188:221-232.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 20% glycerol
Scientific Category
Immunology
NCBI Accession Number
NP_001701
Uniprot Accession Number
P00751
Species
Human
N Terminal Sequence
Ala
AA Sequence
KIVLDPS GSMNIYLVLD GSDSIGASNF TGAKKCLVNL IEKVASYGVK PRYGLVTYAT YPKIWVKVSE ADSSNADWVT KQLNEINYED HKLKSGTNTK KALQAVYSMM SWPDDVPPEG WNRTRHVIIL MTDGLHNMGG DPITVIDEIR DLLYIGKDRK NPREDYLDVY VFGVGPLVNQ VNINALASKK DNEQHVFKVK DMENLEDVFY QMIDESQSLS LCGMVWEHRK GTDYHKQPWQ AKISVIRPSK GHESCMGAVV SEYFVLTAAH CFTVDDKEHS IKVSVGGEKR DLEIEVVLFH PNYNINGKKE AGIPEFYDYD VALIKLKNKL KYGQTIRPIC LPCTEGTTRA LRLPPTTTCQ QQKEELLPAQ DIKALFVSEE EKKLTRKEVY IKNGDKKGSC ERDAQYAPGY DKVKDISEVV TPRFLCTGGV SPYADPNTCR GDSGGPLIVH KRSRFIQVGV ISWGVVDVCK NQKRQKQVPA HARDFHINLF QVLPWLKEKL QDEDLGFL

Related Products

CatalogName
ATGP1877-500Recombinant human Complement Factor D protein
ATGP1877-010Recombinant human Complement Factor D protein
ATGP1877-100Recombinant human Complement Factor D protein
ATGP1877-250Recombinant human Complement Factor D protein
ATGP3098-010Recombinant human Complement Factor D protein
ATGP3098-250Recombinant human Complement Factor D protein
ATGP3098-050Recombinant human Complement Factor D protein
ATGP1877-020Recombinant human Complement Factor D protein
ATGP1877-050Recombinant human Complement Factor D protein
ATGP1413-500Recombinant human PIR-B protein

Alternative Products

CatalogName
abx261019-01Complement Factor D Protein
abx658477-01Human Complement Factor B (CFB) Protein
abx680435-01Human Complement Factor D (Adipsin) Protein
NBP2-22796Recombinant Human Complement Factor B Protein
abx694188-01Human Complement Factor H (CFH) Protein
E53A06129Recombinant Human Complement factor D Protein
abx066074-01Human Complement Factor D (CFD) Protein
abx168664-01Human Complement Factor P (CFP) Protein
abx066080-01Human Complement Factor I (CFI) Protein

Popular Products