Recombinant human Complement Factor D protein

CAT: 0112-ATGP1877-500Size: 500 µgDry Ice: NoHazardous: No
CAT#:0112-ATGP1877-500Size:500 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CFD, also known as adipsin, is involved in the alternative complement pathway of the complement system where it cleaves factor B. This protein is a member of the trypsin family of peptidases. It is a component of the alternative complement pathway best known for its role in humoral suppression of infectious agents. It is also a serine protease that is secreted by adipocytes into the bloodstream. Finally, it has a high level of expression in fat, suggesting a role for adipose tissue in immune system biology. Recombinant human CFD protein, fused to His-tag at N-terminus, was expressed in E. coli.
Product Name Alternative
Complement factor D, DF, AND, PFD, ADIPSIN
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
26.6 kDa (249aa)
Additionnal Information
Complement Factor D, Complement factor D, DF, AND, PFD, ADIPSIN, ATGP1877-10 µg, ATGP1877-20 µg, ATGP1877-50 µg, ATGP1877-100 µg, ATGP1877-250 µg, ATGP1877-500 µg, ATGP1877-1 mg, ATGP1877-10, ATGP1877-20, ATGP1877-50, ATGP1877-100, ATGP1877-250, ATGP1877-500, ATGP1877-1
References & Citations
Narayana SV. et al. (1994) J Mol Biol. 235:695-708.; ; Ronti T. et al. (2006) Clin Endocrinol (Oxf) . 64:355-365.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.4M urea
Scientific Category
Immunology
NCBI Accession Number
NP_001919
Uniprot Accession Number
P00746
Species
Human
AA Sequence
MGSSHHHHHH SSGLVPRGSH MILGGREAEA HARPYMASVQ LNGAHLCGGV LVAEQWVLSA AHCLEDAADG KVQVLLGAHS LSQPEPSKRL YDVLRAVPHP DSQPDTIDHD LLLLQLSEKA TLGPAVRPLP WQRVDRDVAP GTLCDVAGWG IVNHAGRRPD SLQHVLLPVL DRATCNRRTH HDGAITERLM CAESNRRDSC KGDSGGPLVC GGVLEGVVTS GSRVCGNRKK PGIYTRVASY AAWIDSVLA

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