Recombinant human Complement Factor D protein

CAT: 0112-ATGP3098-050Size: 50 µgDry Ice: NoHazardous: No
CAT#:0112-ATGP3098-050Size:50 µg
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Description
CFD, also known as Complement factor D preproprotein, is a serine protease that stimulates glucose transport for triglyceride accumulation in fats cells and inhibits lipolysis. There are two antiparallel beta-barrel domains with each barrel containing six beta-strands with the same typology in all enzymes. The major difference in backbone structure between Factor D and the other serine proteases of the chymotrpsin family is in the surface loops connecting the secondary structural elements. Factor D displays different conformations of major catalytic and substrate-binding residues typically found in the chrotrypsin family. Recombinant human CFD, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Name Alternative
Complement factor D preproprotein, ADIPSIN, ADN, DF, PFD
Expression System
Baculovirus
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 95% by SDS-PAGE
Molecular Weight
26.01 kDa (241aa) confirmed by MALDI-TOF
Additionnal Information
Complement Factor D, ATGP3098-10 µg, ATGP3098-20 µg, ATGP3098-50 µg, ATGP3098-100 µg, ATGP3098-250 µg, ATGP3098-500 µg, ATGP3098-1 mg, ATGP3098-10, ATGP3098-20, ATGP3098-50, ATGP3098-100, ATGP3098-250, ATGP3098-500, ATGP3098-1
References & Citations
Ronti T. et al. (2006) Clin. Endocrinol. 64 (4) :355-65.; ; Volanakis JE. et al. (1996) . Protein Sci. 5 (4) :553-64.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4)
Scientific Category
Immunology
NCBI Accession Number
NP_001919.2
Uniprot Accession Number
P00746
Species
Human

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