Products for Research Use Only
RegisterLogin

Recombinant human PGAM1 protein

CAT: 0112-ATGP3426-250Size: 250 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0112-ATGP3426-250Size:250 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
PGAM1 belongs to the phosphoglycerate mutase family. This protein is important components of glucose and 2, 3-BPGA (2, 3-bisphosphoglycerate) metabolism and catalyzes the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway. The PGAM is a dimeric enzyme containing, in different tissues, different proportions of a slow-migrating muscle (MM) isozyme, a fast-migrating brain (BB) isozyme, and a hybrid form (MB) . Mutations in this protein cause muscle phosphoglycerate mutase efficiency, also known as glycogen storage disease X. Recombinant human PGAM protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Specifications
Specific activity is >300 units/mg, in which One unit will convert 1.0 umole of 3-phosphoglycerate to 2-phosphoglcerate per minute at pH 7.6 at 37C.
Product Name Alternative
Phosphoglycerate mutase 1, Phosphoglycerate mutase isozyme B, PGAM-B, PGAMA
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Enzyme Activity
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Bioactivity
Specific activity is >300unit/mg, in which one unit will convert 1.0 umole of 3-phosphoglycerate to 2-phosphoglcerate per minute at pH 7.6 at 37C.
Molecular Weight
30.9 kDa (274aa) confirmed by MALDI-TOF
Additionnal Information
PGAM1, Phosphoglycerate mutase 1, Phosphoglycerate mutase isozyme B, PGAM-B, PGAMA, ATGP3426-10 µg, ATGP3426-20 µg, ATGP3426-50 µg, ATGP3426-100 µg, ATGP3426-250 µg, ATGP3426-500 µg, ATGP3426-1 mg, ATGP3426-10, ATGP3426-20, ATGP3426-50, ATGP3426-100, ATGP3426-250, ATGP3426-500, ATGP3426-1
References & Citations
Sakoda S., et al. (1988) J Biol Chem. 263 (32) :16899-905. ; ; Junien C., et al. (1982) Ann Genet. 25 (1) :25-7.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 1mM DTT
Scientific Category
Cancer
NCBI Accession Number
NP_002620.1
Uniprot Accession Number
P18669
Species
Human
AA Sequence
MAAYKLVLIR HGESAWNLEN RFSGWYDADL SPAGHEEAKR GGQALRDAGY EFDICFTSVQ KRAIRTLWTV LDAIDQMWLP VVRTWRLNER HYGGLTGLNK AETAAKHGEA QVKIWRRSYD VPPPPMEPDH PFYSNISKDR RYADLTEDQL PSCESLKDTI ARALPFWNEE IVPQIKEGKR VLIAAHGNSL RGIVKHLEGL SEEAIMELNL PTGIPIVYEL DKNLKPIKPM QFLGDEETVR KAMEAVAAQG KAKK

Related Products

CatalogName
ATGP3427-004Recombinant mouse PGAM1 protein
ATGP3427-020Recombinant mouse PGAM1 protein
ATGP1496-500Recombinant mouse PGAM1 protein
ATGP1496-100Recombinant mouse PGAM1 protein
ATGP1496-020Recombinant mouse PGAM1 protein
ATGP3427-100Recombinant mouse PGAM1 protein
ATGA0352-100Human PGAM1 antibody
ATGA0352-050Human PGAM1 antibody
ATGP1427-020Recombinant human PGAM2 protein
ATGP1427-010Recombinant human PGAM2 protein

Alternative Products

CatalogName
ARP3355-01Recombinant Human PGAM1 Protein
PPT-14518Human PGAM1 Recombinant Protein
RP082920PGAM1 Recombinant Protein (Human)
TP726429PGAM1 Human Recombinant Protein
OPCD06137-200UGPGAM1 Recombinant Protein
GTR18894006-01Recombinant Human PGAM1
TP304054LPGAM1 (NM_002629) Human Recombinant Protein
GTR18983497-01Human PGAM1 Protein
PROTQ9DBJ1-20ugMouse PGAM1 Recombinant Protein
NBP1-99029-0.5mgRecombinant Mouse PGAM1 Protein

Popular Products