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Recombinant human Prohibitin 2 protein

CAT: 0112-ATGP2184-020Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP2184-020Size:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PHB2 acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases by similarity. This protein functions as an estrogen receptor (ER) -selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. PHB2 competes with NCOA1 for modulation of ER transcriptional activity. It is probably involved in regulating mitochondrial respiration activity and in aging. Recombinant human PHB2 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Product Name Alternative
Prohibitin 2, Bap37, p22, B cell receptor associated protein 37, BAP, BCAP37, PNAS-141, REA, PHB2
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
35.7 kDa (322aa)
Additionnal Information
B cell receptor associated protein 37, BAP, BAP 37, BAP37, BCAP 37, BCAP37, p22, PHB2, PNAS 141, PNAS141, PNAS-141, Prohibitin 2, Prohibitin2, REA, ATGP2184-10 µg, ATGP2184-20 µg, ATGP2184-50 µg, ATGP2184-100 µg, ATGP2184-250 µg, ATGP2184-500 µg, ATGP2184-1 mg, ATGP2184-010, ATGP2184-020, ATGP2184-050, ATGP2184-100, ATGP2184-250, ATGP2184-500, ATGP2184-01M
References & Citations
Kategaya, L.S., et al. (2012) PLoS ONE 7 (2), E31987; ; Emerson, V., et al. (2010) J. Virol. 84 (3), 1355-1365
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M UREA, 10% glycerol
Scientific Category
Signal Transduction
NCBI Accession Number
NP_001138303.1
Uniprot Accession Number
Q99623
Species
Human
AA Sequence
MAQNLKD LAGRLPAGPR GMGTALKLLL GAGAVAYGVR ESVFTVEGGH RAIFFNRIGG VQQDTILAEG LHFRIPWFQY PIIYDIRARP RKISSPTGSK DLQMVNISLR VLSRPNAQEL PSMYQRLGLD YEERVLPSIV NEVLKSVVAK FNASQLITQR AQVSLLIRRE LTERAKDFSL ILDDVAITEL SFSREYTAAV EAKQVAQQEA QRAQFLVEKA KQEQRQKIVQ AEGEAEAAKM LGEALSKNPG YIKLRKIRAA QNISKTIATS QNRIYLTADN LVLNLQDESF TRGSDSLIKG KK

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