Products for Research Use Only
RegisterLogin

Recombinant human PRNP protein

CAT: 0112-ATGP2013-100Size: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0112-ATGP2013-100Size:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Prion protein, also known as PRNP, is a ubiquitous membrane glycoprotein whose abnormal self-replicating, misfolded form is widely believed to cause several central nervous system disorders, collectively known as Transmissible Spongiform Encephalopathies (TSE) . This protein contains a highly unstable region of five tandem octapeptide repeat. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease, fatal familial insomnia, Gerstmann-Straussler disease, Huntington disease-like 1, and kuru. Recombinant human PRNP protein, fused to His-tag at N-terminus, was expressed in E. coli.
Product Name Alternative
Prion protein preproprotein, Prion protein preproprotein, ASCR, CD230, CJD, GSS, MGC26679, prion, PRIP, PrP, PrP27-30, PrP33-35C, PrPc
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
0.25 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
25 kDa (229aa)
Additionnal Information
PRNP, ATGP2013-10 µg, ATGP2013-20 µg, ATGP2013-50 µg, ATGP2013-100 µg, ATGP2013-250 µg, ATGP2013-500 µg, ATGP2013-1 mg, ATGP2013-10, ATGP2013-20, ATGP2013-50, ATGP2013-100, ATGP2013-250, ATGP2013-500, ATGP2013-1
References & Citations
Weiss S., et al. (1996) Biochem Biophys Res Commun. 219:173-179.; ; Lee I Y., et al. (1998) Genome Res. 8:1022-1037.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol
Scientific Category
Neuroscience
NCBI Accession Number
AAH12844
Uniprot Accession Number
P04156
Species
Human
AA Sequence
KKRPKPGGW NTGGSRYPGQ GSPGGNRYPP QGGGGWGQPH GGGWGQPHGG GWGQPHGGGW GQPHGGGWGQ GGGTHSQWNK PSKPKTNMKH MAGAAAAGAV VGGLGGYVLG SAMSRPIIHF GSDYEDRYYR ENMHRYPNQV YYRPMDEYSN QNNFVHDCVN ITIKQHTVTT TTKGENFTET DVKMMERVVE QMCITQYERE SQAYYQRGS

Related Products

CatalogName
ATGP1924-100Recombinant human PRND protein
ATGP1924-020Recombinant human PRND protein
ATGP1924-004Recombinant human PRND protein
ATGP1314-250Recombinant human RPS7 protein
ATGP1314-050Recombinant human RPS7 protein
ATGP1314-010Recombinant human RPS7 protein
ATGP1312-100Recombinant human MYL4 protein
ATGP1312-020Recombinant human MYL4 protein
ATGP1311-100Recombinant human RBBP9 protein
ATGP1311-020Recombinant human RBBP9 protein

Alternative Products

CatalogName
PROTP04156-100ugHuman PRNP Recombinant Protein
ARP3518-01Recombinant Human PRNP Protein
RP024682PRNP Recombinant Protein (Human)
OPCA01799-20UGPrnp Recombinant Protein
RPU43414-01Recombinant Human Prion Protein (PRNP)
PPT-11337Human CD230/PRNP Recombinant Protein
156444-01Prion Protein (PRNP) Recombinant, Human
GTR18982035-01Human PRNP Protein
RP164672PRNP Recombinant Protein (Mouse)
MBS2018766-01Recombinant Prion Protein (PRNP)

Popular Products