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Human PRNP Recombinant Protein

CAT: 0519-PROTP04156-100ugSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0519-PROTP04156-100ugSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Human PRNP Recombinant Protein expressed in E. coli with His-tag. Sequence domain: 23-230aa. Application (s) : SDS-PAGE, Denatured. Denatured protein is most likely not the best option for functional studies. It is better suited for Western Blot (WB) or imaging assays.
Synonyms
Prion protein preproprotein, Prion protein preproprotein, ASCR, CD230, CJD, GSS, MGC26679, prion, PRIP, PrP, PrP27-30, PrP33-35C, PrPc
Gene Name
PRNP
UniProt
P04156
Tag
His-Tag
Source
E. coli
Applications
SDS-PAGE, Denatured
Field of Research
Neuroscience
Purification
> 90% by SDS-PAGE
Concentration
0.25mg/mL (determined by Bradford assay)
Form
Liquid
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long-term storage, aliquot and store at -20°C to -80°C. Avoid repeated freeze-thaw cycles. (Ships with gel ice.)
Observed Molecular Weight
25 kDa (229aa)
Contents
20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

UniProtKB · P04156

Major prion protein

PRIO_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P04156
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
PRNP
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
PrP
EC number
—
Processing
Precursor
Secondary accessions
O60489, P78446, Q15216, Q15221, Q27H91, Q5QPB4, Q8TBG0, Q96E70, Q9UP19
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative initiation

Cellular component

AmyloidCell membraneGolgi apparatusMembrane

Disease

AmyloidosisDisease variant

Biological process

Cell cycleGrowth arrest

Ligand

CopperMetal-bindingZinc

PTM

Disulfide bondGlycoproteinGPI-anchorLipoprotein

Molecular function

Prion

Domain

RepeatSignal

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