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Recombinant human CD2 protein

CAT: 0112-ATGP1878-020Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP1878-020Size:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CD2, also known as T-cell surface antigen T11/Leu-5, is a cell adhesion molecule found on the surface of T cells and natural killer (NK) cells. It interacts with other adhesion molecules, such as lymphocyte function-associated antigen-3 (LFA-3/CD58) in humans, or CD48 in rodents, which are expressed on the surfaces of other cells. In addition to its adhesive properties, CD2 also acts as a co-stimulatory molecule on T and NK cells. CD2 is a specific marker for T cells and NK cells, and can therefore be used in immunohistochemistry to identify the presence of such cells in tissue sections. The great majority of T cell lymphomas and leukaemias also express CD2, making it possible to use the presence of the antigen to distinguish these conditions from B cell neoplasms. Recombinant human CD2 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Product Name Alternative
T-cell surface antigen CD2, SRBC, T11
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
23.8 kDa (209aa)
Additionnal Information
CD2, T-cell surface antigen CD2, SRBC, T11, ATGP1878-10 µg, ATGP1878-20 µg, ATGP1878-50 µg, ATGP1878-100 µg, ATGP1878-250 µg, ATGP1878-500 µg, ATGP1878-1 mg, ATGP1878-10, ATGP1878-20, ATGP1878-50, ATGP1878-100, ATGP1878-250, ATGP1878-500, ATGP1878-1
References & Citations
Wilkins AL. et al. (2003) Curr Protein Pept Sci. 4:367-373.; ; Yang JJ. et al. (2001) Curr Protein Pept Sci. 2:1-17.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.4M urea
Scientific Category
Stem Cell
NCBI Accession Number
NP_001758
Uniprot Accession Number
P06729
Species
Human
AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSMKEITNA LETWGALGQD INLDIPSFQM SDDIDDIKWE KTSDKKKIAQ FRKEKETFKE KDTYKLFKNG TLKIKHLKTD DQDIYKVSIY DTKGKNVLEK IFDLKIQERV SKPKISWTCI NTTLTCEVMN GTDPELNLYQ DGKHLKLSQR VITHKWTTSL SAKFKCTAGN KVSKESSVEP VSCPEKGLD

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