Products for Research Use Only
RegisterLogin

Recombinant human ATF3 protein

CAT: 0112-ATGP1127-500Size: 500 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0112-ATGP1127-500Size:500 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
ATF3 (activating transcription factor 3) is a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Multiple transcript variants encoding two different isoforms have been found for this gene. The longer isoform represses rather than activates transcription from promoters with ATF binding elements. The shorter isoform (deltaZip2) lacks the leucine zipper protein-dimerization motif and does not bind to DNA, and it stimulates transcription, it is presumed, by sequestering inhibitory co-factors away from the promoter.
Product Name Alternative
Activating transcription factor 3, ATF3deltaZip3, cAMP dependent transcription factor ATF3, Cyclic AMP dependent transcription factor ATF3, Cyclic AMP-dependent transcription factor ATF-3
Expression System
E.coli
Antigen Species
Human
Tag
Non-Tagged
Applications
SDS-PAGE, Denatured
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
20.6 kDa (181aa)
Additionnal Information
ATF3, Activating transcription factor 3, ATF3deltaZip2, ATF3deltaZip2c, ATF3deltaZip3, cAMP dependent transcription factor ATF3, Cyclic AMP dependent transcription factor ATF3, Cyclic AMP-dependent transcription factor ATF-3, ATGP1127-10 µg, ATGP1127-20 µg, ATGP1127-50 µg, ATGP1127-100 µg, ATGP1127-250 µg, ATGP1127-500 µg, ATGP1127-1 mg, ATGP1127-10, ATGP1127-20, ATGP1127-50, ATGP1127-100, ATGP1127-250, ATGP1127-500, ATGP1127-1
References & Citations
Lv D., et al. (2011) IuBMB Life. 63 (1) :62-9. ; ; Chen BP., et al. (1994) J Biol Chem 269 (22) : 15819-26.
Other References
Sato A, et al. Role of activating transcription factor 3 protein ATF3 in necrosis and apoptosis induced by 5-fluoro-2-deoxyuridine. (FEBS J. 2014) {https://pubmed.ncbi.nlm.nih.gov/24529083/}
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 2M urea, 20% glycerol
Scientific Category
Signal Transduction
NCBI Accession Number
NP_001665
Uniprot Accession Number
P18847
Species
Human
AA Sequence
MMLQHPGQVS ASEVSASAIV PCLSPPGSLV FEDFANLTPF VKEELRFAIQ NKHLCHRMSS ALESVTVSDR PLGVSITKAE VAPEEDERKK RRRERNKIAA AKCRNKKKEK TECLQKESEK LESVNAELKA QIEELKNEKQ HLIYMLNLHR PTCIVRAQNG RTPEDERNLF IQQIKEGTLQ S

Related Products

CatalogName
ATGP1138-050Recombinant human ATF4 protein
ATGP1138-010Recombinant human ATF4 protein
ATGP1374-050Recombinant human ATF1 protein
ATGP1374-010Recombinant human ATF1 protein
ATGP1138-250Recombinant human ATF4 protein
ATGP1374-250Recombinant human ATF1 protein
ATGP1320-050Recombinant human PSMA8 protein
ATGP1315-500Recombinant human MRGBP protein
ATGP1315-100Recombinant human MRGBP protein
ATGP1312-500Recombinant human MYL4 protein

Alternative Products

CatalogName
PROTP18847-01Human ATF3 Recombinant Protein
ARP1259-01Recombinant Human ATF3 Protein
RP002170ATF3 Recombinant Protein (Human)
32-2943-20ATF3 Recombinant Protein
PH32491E6ATF3 (NM_001030287) Human Recombinant Protein
GTR18883850-01Human ATF3 protein

Popular Products