Recombinant human CHMP2B protein

• Description :

  CHMP2B belongs to the vacuolar sorting protein family. It is a component of the ESCRT-III complex. This complex is crucial for sorting endosomal articles into multivesicular bodies (MVBs), and are also required for the formation of these bodies. CHMP2B widely expressed in brain, heart, skeletal muscle, small intestine, pancreas, lung, placenta and leukocytes. Recombinant human CHMP2B protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

• Product Name Alternative :

  Charged multivesicular body protein 2B, Charged multivesicular body protein 2b, CHMP2.5, Chromatin-modifying protein 2b, CHMP2b, Vacuolar protein sorting-associated protein 2-2, Vps2-2, hVps2-2

• Expression System :

  E.coli

• Antigen Species :

  Human

• Tag :

  His-Tag

• Applications :

  SDS-PAGE

• Concentration :

  0.5 mg/mL (determined by Bradford assay)

• Purity :

  > 90% by SDS-PAGE

• Molecular Weight :

  26.1 kDa (233aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)

• Additionnal Information :

  CHMP2B, Chromatin modifying protein 2B, DMT1, VPS2B, VPS2-2, CHMP2.5, DKFZp564O123, ATGP1115-10 µg, ATGP1115-20 µg, ATGP1115-50 µg, ATGP1115-100 µg, ATGP1115-250 µg, ATGP1115-500 µg, ATGP1115-1 mg, ATGP1115-10, ATGP1115-20, ATGP1115-50, ATGP1115-100, ATGP1115-250, ATGP1115-500, ATGP1115-1

• References & Citations :

  Rizzu P., et al. (2006) Am J Med Genet B Neuropsychiatr Genet. 141B (8) :944-6.; ; Stuchell-Brereton MD., et al. (2007) Nature. 449 (7163) :740-4.

• Storage Conditions :

  Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

• Formulation :

  Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 1mM DTT, 0.1M NaCl.

• Scientific Category :

  Neuroscience

• NCBI Accession Number :

  NP_054762.2

• Uniprot Accession Number :

  Q9UQN3

• Species :

  Human

• AA Sequence :

  MASLFKKKTV DDVIKEQNRE LRGTQRAIIR DRAALEKQEK QLELEIKKMA KIGNKEACKV LAKQLVHLRK QKTRTFAVSS KVTSMSTQTK VMNSQMKMAG AMSTTAKTMQ AVNKKMDPQK TLQTMQNFQK ENMKMEMTEE MINDTLDDIF DGSDDEEESQ DIVNQVLDEI GIEISGKMAK APSAARSLPS ASTSKATISD EEIERQLKAL GVD