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Recombinant human RAB3D protein

CAT: 0112-ATGP1102-500Size: 500 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP1102-500Size:500 µg
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Description
Ras-related protein Rab-3D, also known as GOV, is a member of the Ras superfamily of small Rab GTPases. Rab proteins play an important role for, either in endocytosis or in biosynthetic protein transport. Rab3D mRNA is predominantly expressed in white adipose tissue and, coincident with GLuT4, increases upon differentiation of 3T3-L1 broblasts into insulin-responsive adipocytes. Rab3D displays close structural similarities with Rab 3A, an isoform which has been functionally implicated in regulated exocytosis in various cell types. Recombinant human Rab3D protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Name Alternative
RAB3D member RAS oncogene family, Ras-related protein Rab-3D, Rab3D upregulated with myeloid differentiation, glioblastoma overexpressed GOV, RAB16, D2-2, RAD3D
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
26.4 kDa (239aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
Additionnal Information
RAB3D, Ras-related protein Rab-3D, GOV, RAB16, ATGP1102-10 µg, ATGP1102-20 µg, ATGP1102-50 µg, ATGP1102-100 µg, ATGP1102-250 µg, ATGP1102-500 µg, ATGP1102-1 mg, ATGP1102-10, ATGP1102-20, ATGP1102-50, ATGP1102-100, ATGP1102-250, ATGP1102-500, ATGP1102-1
References & Citations
Zahraoui A., et al. (1989) J Biol Chem. 264:12934-12401.; ; Baldini G., et al. (1992) Proc Natl Acad Sci. 89:5049-5052.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 30% glycerol, 0.2M NaCl
Scientific Category
Signal Transduction
NCBI Accession Number
NP_004274
Uniprot Accession Number
O95716
Species
Human
AA Sequence
MASAGDTQAG PRDAADQNFD YMFKLLLIGN SSVGKTSFLF RYADDSFTPA FVSTVGIDFK VKTVYRHDKR IKLQIWDTAG QERYRTITTA YYRGAMGFLL MYDIANQESF AAVQDWATQI KTYSWDNAQV ILVGNKCDLE DERVVPAEDG RRLADDLGFE FFEASAKENI NVKQVFERLV DVICEKMNES LEPSSSSGSN GKGPAVGDAP APQPSSCSC