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Recombinant human GSKIP protein

CAT: 0112-ATGP1007-100Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP1007-100Size:100 µg
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Description
GSKIP (GSK3 beta interaction protein) is defined as a naturally occurring protein that is homologous with the GSK3beta interaction domain of Axin and is able to negatively regulate GSK3beta of the Wnt signaling pathway. GSKIP may affect GSK3beta activity on neurite outgrowth by inhibiting the specific phosphorylation of tau (ser396) . Recombinant human GSKIP protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Name Alternative
GSK3-beta interaction protein
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 95% by SDS-PAGE
Molecular Weight
17.8 kDa (159aa) confirmed by MALDI-TOF
Additionnal Information
GSKIP, GSK3-beta interaction protein, ATGP1007-10 µg, ATGP1007-20 µg, ATGP1007-50 µg, ATGP1007-100 µg, ATGP1007-250 µg, ATGP1007-500 µg, ATGP1007-1 mg, ATGP1007-10, ATGP1007-20, ATGP1007-50, ATGP1007-100, ATGP1007-250, ATGP1007-500, ATGP1007-1
References & Citations
Lin CC, et al. (2009) J Cell Biochem. 108 (6) :1325-36.; ; Chou HY, et al (2006) Biochemistry. 45 (38) :11379-89.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol, 50 mM NaCl
Scientific Category
Metabolism
NCBI Accession Number
NP_057556
Uniprot Accession Number
Q9P0R6
Species
Human
AA Sequence
MGSSHHHHHH SSGLVPRGSH METDCNPMEL SSMSGFEEGS ELNGFEGTDM KDMRLEAEAV VNDVLFAVNN MFVSKSLRCA DDVAYINVET KERNRYCLEL TEAGLKVVGY AFDQVDDHLQ TPYHETVYSL LDTLSPAYRE AFGNALLQRL EALKRDGQS

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