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Recombinant human PCBD1 protein

CAT: 0112-ATGP0699-020Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP0699-020Size:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Pterin-4-alpha-carbinolamine dehydratase precursor, also known as PCBD1, is a component of the phenylalanine hydroxylase (PAH) system and participates in tetrahydrobiopterin biosynthesis. A deficiency of this enzyme leads to hyperphenylalaninemia. The enzyme regulates the homodimerization of the transcription factor hepatocyte nuclear factor 1 (HNF1) . Recombinant human PCBD1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Name Alternative
Pterin-4-alpha-carbinolamine dehydratase, DCOH, PCBD, PCD, PHS
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 95% by SDS-PAGE
Molecular Weight
14.1 kDa (124aa) confirmed by MALDI-TOF
Additionnal Information
PCBD1, Pterin-4-alpha-carbinolamine dehydratase, DCOH, PCBD, PCD, PHS, ATGP0699-10 µg, ATGP0699-20 µg, ATGP0699-50 µg, ATGP0699-100 µg, ATGP0699-250 µg, ATGP0699-500 µg, ATGP0699-1 mg, ATGP0699-10, ATGP0699-20, ATGP0699-50, ATGP0699-100, ATGP0699-250, ATGP0699-500, ATGP0699-1
References & Citations
Schallreuter K u., et al. (2004) Biochem Biophys Res Commun. 315:502-508.; ; Hasse S., et al. (2005) Exp Dermatol. 14:182-187.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol
Scientific Category
Metabolism
NCBI Accession Number
NP_000272
Uniprot Accession Number
P61457
Species
Human
AA Sequence
MAGKAHRLSA EERDQLLPNL RAVGWNELEG RDAIFKQFHF KDFNRAFGFM TRVALQAEKL DHHPEWFNVY NKVHITLSTH ECAGLSERDI NLASFIEQVA VSMT

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