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PCBD1 cDNA

CAT: 0112-ATGD0121-010Size: 10 µgDry Ice: NoHazardous: No
CAT#: ATGD0121-010Size: 10 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PCBD1 encodes a member of the pterin-4-alpha-carbinolamine dehydratase family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The encoded protein functions as both a dehydratase involved in tetrahydrobiopterin biosynthesis, and as a cofactor for HNF1A-dependent transcription. A deficiency of this enzyme leads to hyperphenylalaninemia. Alternative splicing results in multiple transcript variants.
Product Name Alternative
DCOH, PCBD, PCD, PHS
Chromosomal Location
10q22
Antigen Species
Human
Vector Type
PATGen (puc19-derived cloning vector)
Sequence
ATGGCTGGCAAAGCACACAGGCTGAGCGCTGAGGAGAGGGACCAGCTGCTGCCAAACCTGAGGGCTGTGGGGTGGAATGAGCTGGAAGGCCGTGATGCCATCTTCAAGCAGTTTCATTTCAAAGACTTCAACAGGGCCTTTGGGTTCATGACAAGAGTGGCCCTGCAGGCTGAGAAACTGGACCACCATCCTGAATGGTTTAACGTGTACAACAAGGTCCACATCACGCTGAGCACCCATGAGTGTGCCGGCCTTTCAGAACGGGACATAAACCTGGCCAGCTTCATCGAACAAGTAGCAGTGTCCATGACATAG
Additionnal Information
PCBD1, DCOH, PCBD, PCD, PHS, PCBD1, ATGD0121-10 µg, ATGD0121-20 µg, ATGD0121-50 µg, ATGD0121-100 µg, ATGD0121-250 µg, ATGD0121-500 µg, ATGD0121-1 mg, ATGD0121-10, ATGD0121-20, ATGD0121-50, ATGD0121-100, ATGD0121-250, ATGD0121-500, ATGD0121-1
Storage Conditions
Store the plasmid at -20C.
Formulation
Lyophilized
Scientific Category
Metabolism
Omim
126090
NCBI Accession Number
NP_000272.1
Species
Human
Preparation
1. Centrifuge at 7000rpm for 1 minute.; ;2. Carefully open the vial and add 100 µL of sterile water to dissolve the DNA.; ; Each tube contains approximately 10 µg of lyophilized plasmid.
RNA Reference
NM_000281.3
DNA Size
315bp
Vector Description
This shuttle vector contains the complete ORF. It is inseted BamH I to Xho I. The gene insert contains multiple cloning sites which can be used to easily cut and transfer the gene and recombination site into your expression vector.

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