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Recombinant human TES protein

CAT: 0112-ATGP0684-050Size: 50 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP0684-050Size:50 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TES is a tumor suppressor protein and may play role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. This protein localizes to cell-cell contacts and actin stress fibres, and interacts with a variety of cytoskeletal proteins including Zyxin, Mena, VASP, Talin and Actin. The ability of TES to associate with alpha-actinin, paxillin and Zyxin is dependent on the conformational state of the molecule. Recombinant human TES protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Name Alternative
Testin, TESS, TESS-2, Testin
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
50.1 kDa (441aa) confirmed by MALDI-TOF
Additionnal Information
TES, Testin, TESS, TESS-2, Testin, ATGP0684-10 µg, ATGP0684-20 µg, ATGP0684-50 µg, ATGP0684-100 µg, ATGP0684-250 µg, ATGP0684-500 µg, ATGP0684-1 mg, ATGP0684-10, ATGP0684-20, ATGP0684-50, ATGP0684-100, ATGP0684-250, ATGP0684-500, ATGP0684-1
References & Citations
Qiu H., et al. (2010) Cancer Sci. 101 (5) :1255-60.; ; Sato T., et al. (2003) J Biol Chem. 278 (48) :47534-44.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 1mM DTT, 10% glycerol
Scientific Category
Cancer
NCBI Accession Number
NP_056456
Uniprot Accession Number
Q9UGI8
Species
Human
AA Sequence
MDLENKVKKM GLGHEQGFGA PCLKCKEKCE GFELHFWRKI CRNCKCGQEE HDVLLSNEED RKVGKLFEDT KYTTLIAKLK SDGIPMYKRN VMILTNPVAA KKNVSINTVT YEWAPPVQNQ ALARQYMQML PKEKQPVAGS EGAQYRKKQL AKQLPAHDQD PSKCHELSPR EVKEMEQFVK KYKSEALGVG DVKLPCEMDA QGPKQMNIPG GDRSTPAAVG AMEDKSAEHK RTQYSCYCCK LSMKEGDPAI YAERAGYDKL WHPACFVCST CHELLVDMIY FWKNEKLYCG RHYCDSEKPR CAGCDELIFS NEYTQAENQN WHLKHFCCFD CDSILAGEIY VMVNDKPVCK PCYVKNHAVV CQGCHNAIDP EVQRVTYNNF SWHASTECFL CSCCSKCLIG QKFMPVEGMV FCSVECKKRM S

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