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Recombinant human TRAF-1 protein

CAT: 0112-ATGP0571-100Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP0571-100Size:100 µg
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Description
TRAF1, also known as TNF receptor-associated factor 1, belongs to TNF receptor superfamily. This protein and TRAF2 form a heterodimeric complex, which is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The complex also interacts with inhibitor-of-apoptosis proteins (IAPs), and thus mediates the anti-apoptotic signals from TNF receptors. Recombinant human TRAF1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Name Alternative
TNF receptor-associated factor 1, EBI6, TNF receptor-associated factor 1 4732496E14Rik, EBV induced protein 6, Epstein-Barr virus-induced protein 6, Tnf receptor associated factor 1, TRAF 1.
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 95% by SDS-PAGE
Molecular Weight
19.5 kDa (172aa) confirmed by MALDI-TOF
Additionnal Information
TRAF1, TNF receptor-associated factor 1, EBI6, TNF receptor-associated factor 1 4732496E14Rik, EBV induced protein 6, Epstein-Barr virus-induced protein 6, Tnf receptor associated factor 1, TRAF 1., ATGP0571-10 µg, ATGP0571-20 µg, ATGP0571-50 µg, ATGP0571-100 µg, ATGP0571-250 µg, ATGP0571-500 µg, ATGP0571-1 mg, ATGP0571-10, ATGP0571-20, ATGP0571-50, ATGP0571-100, ATGP0571-250, ATGP0571-500, ATGP0571-1
References & Citations
Ansieau S. et al. (1996) Proc Natl Acad Sci u S A. 93 (24) :14053-8.; ; Leo E, et al. (2001) J Biol Chem. 276 (11) :8087-93;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1M NaCl,1mM DTT
Scientific Category
Apoptosis
NCBI Accession Number
NP_005649
Uniprot Accession Number
Q13077
Species
Human
AA Sequence
MDGTFLWKIT NVTRRCHESA CGRTVSLFSP AFYTAKYGYK LCLRLYLNGD GTGKRTHLSL FIVIMRGEYD ALLPWPFRNK VTFMLLDQNN REHAIDAFRP DLSSASFQRP QSETNVASGC PLFFPLSKLQ SPKHAYVKDD TMFLKCIVET ST