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Recombinant human FBPase 1 protein

CAT: 0112-ATGP0408-020Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP0408-020Size:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Fructose-1, 6-bisphosphatase 1 (FBP1) is a gluconeogenesis regulatory enzyme, catalyzes the hydrolysis of fructose 1, 6-bisphosphate to fructose 6-phosphate and inorganic phosphate. Fructose-1, 6-diphosphatase deficiency is associated with hypoglycemia and metabolic acidosis. Recombinant FBP1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Name Alternative
FBPase1, FBP, FBP1, D fructose 1 6 bisphosphate 1 phosphohydrolase 1, EC 3.1.3.11, FBP 1, FBPase 1, Fructose 1 6 bisphosphatase 1 Fructose bisphosphatase 1, Growth inhibiting protein 17, Liver fructose bisphosphatase.
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
39.0 kDa (358aa) confirmed by MALDI-TOF
Additionnal Information
FBPase1, FBPase1, FBP, FBP1, D fructose 1 6 bisphosphate 1 phosphohydrolase 1, EC 3.1.3.11, FBP 1, FBPase 1, Fructose 1 6 bisphosphatase 1 Fructose bisphosphatase 1, Growth inhibiting protein 17, Liver fructose bisphosphatase., ATGP0408-10 µg, ATGP0408-20 µg, ATGP0408-50 µg, ATGP0408-100 µg, ATGP0408-250 µg, ATGP0408-500 µg, ATGP0408-1 mg, ATGP0408-10, ATGP0408-20, ATGP0408-50, ATGP0408-100, ATGP0408-250, ATGP0408-500, ATGP0408-1
References & Citations
Rabenhorst u., et al. (2009) Hepatology. 50 (4) :1121-9. ; ; Hirota K., et al. (2008) Nature. 456 (7218) :130-4.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol
Scientific Category
Metabolism
NCBI Accession Number
NP_000498.2
Uniprot Accession Number
P09467
Species
Human
AA Sequence
MADQAPFDTD VNTLTRFVME EGRKARGTGE LTQLLNSLCT AVKAISSAVR KAGIAHLYGI AGSTNVTGDQ VKKLDVLSND LVMNMLKSSF ATCVLVSEED KHAIIVEPEK RGKYVVCFDP LDGSSNIDCL VSVGTIFGIY RKKSTDEPSE KDALQPGRNL VAAGYALYGS ATMLVLAMDC GVNCFMLDPA IGEFILVDKD VKIKKKGKIY SLNEGYARDF DPAVTEYIQR KKFPPDNSAP YGARYVGSMV ADVHRTLVYG GIFLYPANKK SPNGKLRLLY ECNPMAYVME KAGGMATTGK EAVLDVIPTD IHQRAPVILG SPDDVLEFLK VYEKHSAQ

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