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Recombinant human TRAX protein

CAT: 0112-ATGP1819-020Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP1819-020Size:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TSNAX is a protein which specifically interacts with translin, a DNA-binding protein that binds consensus sequences at breakpoint junctions of chromosomal translocations. The protein contains bipartite nuclear targeting sequences that may provide nuclear transport for translin, which lacks any nuclear targeting motifs. Recombinant human TSNAX protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Name Alternative
Translin-associated protein X, TRAX
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.25 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
35 kDa (313aa) confirmed by MALDI-TOF
Additionnal Information
TSNAX, Translin-associated protein X, TRAX, , ATGP1819-10 µg, ATGP1819-20 µg, ATGP1819-50 µg, ATGP1819-100 µg, ATGP1819-250 µg, ATGP1819-500 µg, ATGP1819-1 mg, ATGP1819-010, ATGP1819-020, ATGP1819-050, ATGP1819-100, ATGP1819-250, ATGP1819-500, ATGP1819-01M
References & Citations
Chennathukuzhi VM, Kurihara Y, et al. (2001) . J Biol Chem. 276 (16) :13256-63.; ; Thomson PA, Wray NR, et al. (2005) . Mol Psychiatry. 10 (7) :657-68, 616.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 20% glycerol, 50 mM Imidazole, 0.1mM PMSF
Scientific Category
Epigenomics (Transcription & Translation)
NCBI Accession Number
NP_005990.1
Uniprot Accession Number
Q99598
Species
Human
AA Sequence
MSNKEGS GGFRKRKHDN FPHNQRREGK DVNSSSPVML AFKSFQQELD ARHDKYERLV KLSRDITVES KRTIFLLHRI TSAPDMEDIL TESEIKLDGV RQKIFQVAQE LSGEDMHQFH RAITTGLQEY VEAVSFQHFI KTRSLISMDE INKQLIFTTE DNGKENKTPS SDAQDKQFGT WRLRVTPVDY LLGVADLTGE LMRMCINSVG NGDIDTPFEV SQFLRQVYDG FSFIGNTGPY EVSKKLYTLK QSLAKVENAC YALKVRGSEI PKHMLADVFS VKTEMIDQEE GIS

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