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Recombinant human BAG1 protein

CAT: 0112-ATGP0508-100Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP0508-100Size:100 µg
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Description
BCL2-associated athanogene, also known as BAG1, is a member of the Bcl-2 family of proteins that play varied stimulatory or inhibitory roles in the regulation of programmed cell death. This functions in conjunction with Bcl-2 to inhibit apoptosis. Also, BAG1 has been implicated in age related neurodegenerative diseases as Alzheimer's. It is localized to the cytosol, nucleus or both. Recombinant human BAG1 was expressed in E. coli and purified by using conventional chromatography techniques.
Product Name Alternative
BAG cochaperone 1, BCL2 associated athanogene, BCL2 associated athanogene 1, HAP, RAP46
Expression System
E.coli
Antigen Species
Human
Tag
Non-Tagged
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
25.9 kDa (230aa) confirmed by MALDI-TOF
Additionnal Information
BAG1, BCL2-associated athanogene 1, HAP, RAP46, BCL2-associated athanogene 1 Bag 1, BAG family molecular chaperone regulator 1, BCL 2 associated athanogene, BCL 2 Associated Athanogene 1, BCL 2 binding athanogene 1, BCL2 associated athanogene, BCL2 associated athanogene 1, Glucocorticoid receptor-associated protein RAP46, HAP1, Haptoglobin, RAP 46., ATGP0508-10 µg, ATGP0508-20 µg, ATGP0508-50 µg, ATGP0508-100 µg, ATGP0508-250 µg, ATGP0508-500 µg, ATGP0508-1 mg, ATGP0508-10, ATGP0508-20, ATGP0508-50, ATGP0508-100, ATGP0508-250, ATGP0508-500, ATGP0508-1
References & Citations
Wang HG., et al. (1996) Proc Natl Acad Sci u S A. 93 (14) :7063-8. ; ; Takayama S., et al. (1995) Cell. 80 (2) :279-84.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 7.5) containing 100 mM NaCl, 10% glycerol
Scientific Category
Apoptosis
NCBI Accession Number
NP_001165886
Uniprot Accession Number
Q99933
Species
Human
AA Sequence
MNRSQEVTRD EESTRSEEVT REEMAAAGLT VTVTHSNEKH DLHVTSQQGS SEPVVQDLAQ VVEEVIGVPQ SFQKLIFKGK SLKEMETPLS ALGIQDGCRV MLIGKKNSPQ EEVELKKLKH LEKSVEKIAD QLEELNKELT GIQQGFLPKD LQAEALCKLD RRVKATIEQF MKILEEIDTL ILPENFKDSR LKRKGLVKKV QAFLAECDTV EQNICQETER LQSTNFALAE