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Recombinant human BAG2 protein

CAT: 0112-ATGP0952-500Size: 500 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP0952-500Size:500 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BCL2-associated athanogene 2, also known as BAG2, is a member of the Bag family of proteins. BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain. BAG2 is a major component of the HSC 70/CHIP chaperone-dependent ubiquitin ligase complex and acts to disrupt CHIP-mediated ubiquitylation. Recombinant human BAG2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Name Alternative
BCL2-associated athanogene 2, BAG-2
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 95% by SDS-PAGE
Molecular Weight
25.9 kDa (231aa) confirmed by MALDI-TOF
Additionnal Information
BAG2, BCL2-associated athanogene 2, BAG-2, ATGP0952-10 µg, ATGP0952-20 µg, ATGP0952-50 µg, ATGP0952-100 µg, ATGP0952-250 µg, ATGP0952-500 µg, ATGP0952-1 mg, ATGP0952-10, ATGP0952-20, ATGP0952-50, ATGP0952-100, ATGP0952-250, ATGP0952-500, ATGP0952-1
References & Citations
Takayama S., et al. (1999) J Biol Chem. 274:781-786.; ; Arndt V., et al. (2005) CHIP Mol Biol Cell. 16:5891-5900.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 20% glycerol, 0.1M NaCl
Scientific Category
Heat Shock Proteins
NCBI Accession Number
NP_004273.1
Uniprot Accession Number
O95816
Species
Human
AA Sequence
MAQAKINAKA NEGRFCRSSS MADRSSRLLE SLDQLELRVE ALREAATAVE QEKEILLEMI HSIQNSQDMR QISDGEREEL NLTANRLMGR TLTVEVSVET IRNPQQQESL KHATRIIDEV VNKFLDDLGN AKSHLMSLYS ACSSEVPHGP VDQKFQSIVI GCALEDQKKI KRRLETLLRN IENSDKAIKL LEHSKGAGSK TLQQNAESRF N

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