Products for Research Use Only
RegisterLogin

Human CDC37 antibody

CAT: 0112-ATGA0428-100Size: 100 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0112-ATGA0428-100Size:100 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
The protein encoded by this gene is highly similar to CDC37, a cell division cycle control protein of Saccharomyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF1, MOK, as well as eIF-2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases.
Product Name Alternative
Cell division cycle 37 homolog, P50CDC37, CDC37, Cell division cycle 37 homolog, Cell division cycle 37 homolog S cerevisiae hypothetical protein CDC37, CDC 37, CDC37 cell division cycle 37 homolog, Cdc37 homolog, CDC37 protein, Hsp90 chaperone protein kinase targeting subunit, Hsp90 chaperone protein kinase targeting subunit p50Cdc37, Hsp90 co chaperone Cdc37, p50, p50Cdc37.
Host
Mouse
Antigen Species
Human
Reactivity
Human
Immunogen
Recombinant human CDC37 (1-378aa) purified from E. coli
Clonality
Monoclonal
Isotype
IgG1 κ
Clone
AT3G7
Conjugation
Unconjugated
Applications
ELISA, WB, ICC/IF
Purification Method
By protein-A affinity chromatography
Concentration
1 mg/mL (determined by BCA assay)
Additionnal Information
CDC37, Cell division cycle 37 homolog, P50CDC37, CDC37, Cell division cycle 37 homolog, Cell division cycle 37 homolog S cerevisiae hypothetical protein CDC37, CDC 37, CDC37 cell division cycle 37 homolog, Cdc37 homolog, CDC37 protein, Hsp90 chaperone protein kinase targeting subunit, Hsp90 chaperone protein kinase targeting subunit p50Cdc37, Hsp90 co chaperone Cdc37, p50, p50Cdc37., ATGA0428-10 µg, ATGA0428-20 µg, ATGA0428-50 µg, ATGA0428-100 µg, ATGA0428-250 µg, ATGA0428-500 µg, ATGA0428-1 mg, ATGA0428-10, ATGA0428-20, ATGA0428-50, ATGA0428-100, ATGA0428-250, ATGA0428-500, ATGA0428-1
References & Citations
Quotti Tubi, et al. (2013) J Hematol Oncol. 6: 78.; ; Manni S., et al. (2012) Clin Cancer Res. 18: 1888-900.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
Applications Notes
The antibody has been tested by ELISA, Western blot analysis and ICC/IF to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.
Scientific Category
Cell Cycle
NCBI Accession Number
NP_008996
Uniprot Accession Number
Q16543
WB Description
The cell line and tissue lysates (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human CDC37 antibody (1:1000) . Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. ; ; Lane 1. : Jurkat cell lysate ; ; Lane 2. : A431 cell lysate ; ; Lane 3. : K562 cell lysate ; ; Lane 4. : LnCap cell lysate ; ; Lane 5. : SW480 cell lysate ; ; Lane 6. : HeLa cell lysate ; ; Lane 7. : MCF7 cell lysate ; ; Lane 8. : 293T cell lysate
IF Description
ICC/IF analysis of CDC37 in Balb/3T3 cells line, stained with DAPI (Blue) for nucleus staining and monoclonal anti-human CDC37 antibody (1:100) with goat anti-mouse IgG-Alexa fluor 488 conjugate (Green) .

Related Products

CatalogName
CDC0901-020Recombinant human CDC37 protein
CDC0901-500Recombinant human CDC37 protein
CDC0901-100Recombinant human CDC37 protein
ATGP0710-500Recombinant human UBE2R1/CDC34 protein
ATGP0710-100Recombinant human UBE2R1/CDC34 protein
ATGP0710-020Recombinant human UBE2R1/CDC34 protein
ATGD0073-010CDC34 cDNA
ATGA0604-100Human AGXT antibody
ATGA0583-050Human ACAT1 antibody
ATGA0581-050Human LSM2 antibody

Alternative Products

CatalogName
32881-05111Human CDC37 antibody
32881-05121Human CDC37 antibody (Biotin Conjugate)
PHH28501Anti-Human CDC37 Polyclonal Antibody
32881-05151Human CDC37 AssayLite™ Antibody (RPE Conjugate)
PA84171HU-01Rabbit Anti-Human Cdc37 Polyclonal Antibody
32881-05141Human CDC37 AssayLite™ Antibody (FITC Conjugate)
32881-05171Human CDC37 AssayLite™ Antibody (PerCP Conjugate)
32881-05161Human CDC37 AssayLite™ Antibody (APC Conjugate)
PA87342HU-01Rabbit Anti-Human Cdc37 (phospho Ser13) Polyclonal Antibody
OM303912-01CDC37 Human

Popular Products