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Cucurbit[8]uril

CAT: 0804-HY-103689-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-103689-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cucurbit[8]uril is a potent, low toxicity and orally active supramolecular inducer of protein heterodimerization. Cucurbit[8]uril induces heterodimerization of methylviologen and naphthalene functionalized proteins. Cucurbit[8]uril can induce energy transfer [1][2].
CAS Number
259886-51-6
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Biochemical Assay Reagents
Type
Reference compound
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/cucurbit-8-uril.html
Purity
98.0
Solubility
DMSO : < 1 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C1N(CN(C2=O)[C@]([C@@]3([H])N2CN(C4=O)[C@]([C@@]5([H])N4CN(C6=O)[C@]([C@@]7([H])N6CN8[C@]9([H])N(C%10=O)CN%117)([H])N(C%11=O)CN%125)([H])N(C%12=O)CN3C%13=O)([H])N%13CN%14%15)[C@]%14([H])[C@]%16([H])N1CN(C%17=O)[C@@]([C@]%18([H])N%17CN(C%19=O)[C@@]([C@]%20([H])N%19CN(C%21=O)[C@@]([C@]%22([H])N%21CN%23C8=O)([H])N(C(N%22CN%10[C@]%239[H])=O)CN%24%20)([H])N(C%24=O)CN%18C%25=O)([H])N%25CN%16C%15=O
Molecular Formula
C48H48N32O16
Molecular Weight
1329.10
Precautions
H302, H315, H319, H335
References & Citations
[1]Uhlenheuer DA, et al. Cucurbit[8]uril induced heterodimerization of methylviologen and naphthalene functionalized proteins. Chem Commun (Camb) . 2011;47 (24) :6798-6800.|[2]Uzunova VD, et al. Toxicity of cucurbit[7]uril and cucurbit[8]uril: an exploratory in vitro and in vivo study. Org Biomol Chem. 2010;8 (9) :2037-2042.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported