Thalidomide 5-Pip-C-oxotetrahydropyrimidin-bromophenyl

CAT:

804-HY-159623

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CAS Number: 3024909-50-7
UNSPSC Description: Thalidomide 5-Pip-C-oxotetrahydropyrimidin-bromophenyl is an E3 Ligase Ligand-Linker Conjugate. Thalidomide 5-Pip-C-oxotetrahydropyrimidin-bromophenyl can be used to synthesize PROTAC GSPT1 degrader-2 (HY-159610)[1].
Target Antigen: E3 Ligase Ligand-Linker Conjugates
Type: Reference compound
Related Pathways: PROTAC
Applications: Cancer-programmed cell death
Field of Research: cancer
Assay Protocol: https://www.medchemexpress.com/thalidomide-5-pip-c-oxotetrahydropyrimidin-bromophenyl.html
Smiles: O=C1NC(C(CC1)N2C(C3=CC=C(N4CCC(CC4)CN5C(N(CCC5)C6=CC(Br)=CC=C6)=O)C=C3C2=O)=O)=O
Molecular Weight: 608.48
References & Citations: [1]Tetrahydropyrimidine derivatives as GSPT1 degraders and their preparation. World Intellectual Property Organization, WO2024073871 A1. 2024-04-11.
Shipping Conditions: Room temperature
Clinical Information: No Development Reported

Cat	Name
HY-159623	Thalidomide 5-Pip-C-oxotetrahydropyrimidin-bromophenyl
HY-159622	Boc-Pip-C-oxotetrahydropyrimidin-bromophenyl
HY-159620	Thalidomide 5-azetidine-2C-oxotetrahydropyrimidin-bromophenyl
HY-161208	Deoxy-thalidomide-Pip-C-PIP-boc
HY-161206	Thalidomide-Pip-C-Pip-O-C-boc
HY-159619	Boc-azetidine-2C-oxotetrahydropyrimidin-bromophenyl
HY-161210	Thalidomide-azetidine-C-PIP-C-boc
HY-168724	Thalidomide-piperidine-C-Pip-C2-Pip-C2-OH
HY-161205	Thalidomide-PIP-(R)C-pyrrolidine-boc
HY-161576	Thalidomide-Pip-N-boc

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