Thalidomide-piperidine-C-Pip-C2-Pip-C2-OH

Thalidomide-piperidine-C-Pip-C2-Pip-C2-OH

• UNSPSC Description: Thalidomide-piperidine-C-Pip-C2-Pip-C2-OH (Compound C6) is a conjugate of the linker and E3 ligase ligand, that can be used in synthesis of PROTAC PARP1 degrader-30 (HY-168722)[1].
• Target Antigen: E3 Ligase Ligand-Linker Conjugates; PARP
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage;Epigenetics;PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/thalidomide-piperidine-c-pip-c2-pip-c2-oh.html
• Smiles: OCCC1CCN(CCC2CCN(CC3CCN(C4=CC5=C(C(N(C6CCC(NC6=O)=O)C5=O)=O)C=C4)CC3)CC2)CC1
• Molecular Weight: 593.76
• References & Citations: [1]Wu M, et al., Discovery of a potent PARP1 PROTAC as a chemosensitizer for the treatment of colorectal cancer. Eur J Med Chem. 2025 Jan 15;282:117062.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported