Demethoxycurcumin-d4

• Description :

  Demethoxycurcumin-d4 is the deuterium labeled Demethoxycurcumin. Demethoxycurcumin (Curcumin II) is a major active curcuminoid; possess anti-inflammatory properties[1].

• Product Name Alternative :

  Curcumin II-d4; Desmethoxycurcumin-d4; Monodemethoxycurcumin-d4

• UNSPSC :

  12352005

• Hazard Statement :

  H400

• Target :

  Apoptosis; Autophagy; Bacterial

• Type :

  Isotope-Labeled Compounds

• Related Pathways :

  Anti-infection; Apoptosis; Autophagy

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Purity :

  98.89

• Solubility :

  10 mM in DMSO|DMSO : 100mg/mL (ultrasonic)

• Smiles :

  O=C(CC(/C=C/C1=C([2H])C([2H])=C(O)C([2H])=C1[2H])=O)/C=C/C2=CC=C(O)C(OC)=C2

• Molecular Formula :

  C20H14D4O5

• Molecular Weight :

  342.38

• Precautions :

  H400

• References & Citations :

  [1]Somchit M, et al. Demethoxycurcumin from Curcuma longa rhizome suppresses iNOS induction in an in vitro inflamed human intestinal mucosa model. Asian Pac J Cancer Prev. 2014;15 (4) :1807-10.|[2]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-223.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Isotope-Labeled Compounds

• Clinical Information :

  No Development Reported