Demethoxycurcumin (Standard)

CAT: 0804-HY-N0006R-01Size: 5 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0804-HY-N0006R-01Size:5 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

Description

Demethoxycurcumin (Standard) is the analytical standard of Demethoxycurcumin. This product is intended for research and analytical applications. Demethoxycurcumin is one of the main active ingredients of curcumin, which has anti-inflammatory, antioxidant, antibacterial, anti-cancer and neuroprotective effects. Demethoxycurcumin is orally active. Demethoxycurcumin can be used in inflammation, cancer and Alzheimer's disease research[1][2][3][4][5].

CAS Number

22608-11-3

Product Name Alternative

Curcumin II (Standard) ; Desmethoxycurcumin (Standard) ; Monodemethoxycurcumin (Standard)

UNSPSC

12352005

Hazard Statement

H400

Target

Apoptosis; Bacterial; Cholinesterase (ChE) ; NO Synthase; Reference Standards

Type

Reference Standards

Related Pathways

Anti-infection; Apoptosis; Immunology/Inflammation; Neuronal Signaling; Others

Field of Research

Cancer; Infection; Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/demethoxycurcumin-standard.html

Purity

98.83

Smiles

O=C(CC(/C=C/C1=CC=C(O)C=C1)=O)/C=C/C2=CC=C(O)C(OC)=C2

Molecular Formula

C20H18O5

Molecular Weight

338.36

Precautions

H400

References & Citations

[1]Somchit M, et al. Demethoxycurcumin from Curcuma longa rhizome suppresses iNOS induction in an in vitro inflamed human intestinal mucosa model. Asian Pac J Cancer Prev. 2014;15 (4) :1807-10.|[2]Ko YC, et al. Demethoxycurcumin Alters Gene Expression Associated with DNA Damage, Cell Cycle and Apoptosis in Human Lung Cancer NCI-H460 Cells In Vitro. In Vivo. 2015 01-02;29 (1) :83-94.|[3]Ahmed T, et al. A comparative study of curcuminoids to measure their effect on inflammatory and apoptotic gene expression in an Aβ plus ibotenic acid-infused rat model of Alzheimer's disease. Brain Res. 2011 Jul 11;1400:1-18. |[4]Lim DW, et al. Enhanced Cognitive Effects of Demethoxycurcumin, a Natural Derivative of Curcumin on Scopolamine-Induced Memory Impairment in Mice. Molecules. 2016 Aug 5;21 (8) :1022. |[5]Luo J, et al. Demethoxycurcumin: A potential antimicrobial agent: Exposure by microcalorimetry and modified broth microdilution method[J]. Journal of Thermal Analysis and Calorimetry, 2014, 115: 2331-2338.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, sealed storage, away from light and moisture

Scientific Category

Reference Standards

Chemical Information

Demethoxycurcumin

Demethoxycurcumin is a beta-diketone that is curcumin in which one of the methoxy groups is replaced by hydrogen. It is found in Curcuma zedoaria and Etlingera elatior. It has a role as a metabolite, an antineoplastic agent and an anti-inflammatory agent. It is a polyphenol, an enone, a beta-diketone and a diarylheptanoid.

CAS Number	22608-11-3
PubChem CID	5469424
IUPAC Name	(1E,6E)-1-(4-hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)hepta-1,6-diene-3,5-dione
Molecular Formula	C20H18O5
Molecular Weight	338.4
XLogP	3.3
Topological Polar Surface Area	83.8
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	7
Heavy Atom Count	25
Formal Charge	0
Complexity	502

SMILES

COC1=C(C=CC(=C1)/C=C/C(=O)CC(=O)/C=C/C2=CC=C(C=C2)O)O

InChI

InChI=1S/C20H18O5/c1-25-20-12-15(6-11-19(20)24)5-10-18(23)13-17(22)9-4-14-2-7-16(21)8-3-14/h2-12,21,24H,13H2,1H3/b9-4+,10-5+

InChIKey

HJTVQHVGMGKONQ-LUZURFALSA-N

Chemical Structure

2D Structure

CAS: 22608-11-3

CID: 5469424

Formula: C20H18O5

MW: 338.4

Interactive 3D Structure

Loading 3D structure...

View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	338.4
XLogP3	3.3
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	7
Exact Mass	338.11542367
Monoisotopic Mass	338.11542367
Topological Polar Surface Area	83.8 Å²
Heavy Atom Count	25
Formal Charge	0
Complexity	502
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	2
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Related Products

Catalog	Name
HY-N0006-01	Demethoxycurcumin
HY-N0006S-01	Demethoxycurcumin-d7
HY-N0006S1-01	Demethoxycurcumin-d4
HY-N0006A-01	(E/Z) -Demethoxycurcumin
HY-P1940R	Maculosin (Standard)
HY-N8537R-01	Enfumafungin (Standard)
HY-N8034R	Glychionide A (Standard)
HY-N7848R	Linoleamide (Standard)
HY-N7819R-01	Pristane (Standard)
HY-N7560R-01	Safranal (Standard)

Alternative Products

Catalog	Name
FD20982-01	Demethoxycurcumin
A14545-25	Demethoxycurcumin 25mg
A14545-5	Demethoxycurcumin 5mg
371357	Demethoxycurcumin discontinued
A14545-50	Demethoxycurcumin 50mg
A14545-10	Demethoxycurcumin 10mg

Demethoxycurcumin (Standard)

Chemical Information

Related Products

Alternative Products

Popular Products