2-Boronobenzoic acid

2-Boronobenzoic acid (CAS: 149105-19-1) is a high-purity aromatic boronic acid derivative with carboxyl functional group. This fine chemical appears as white crystalline powder at room temperature, with stable chemical properties, moderate acidity and good solubility in polar solvents. The ortho-substituted carboxyl and boronic acid bifunctional groups endow the molecule with excellent coordination ability and reaction activity. It is a critical dual-functional organic building block widely used in organic cross-coupling synthesis, coordination chemistry and pharmaceutical intermediate preparation.

2-Carboxybenzeneboronic acid, 2-Carboxyphenylboronic acid, o-Carboxyphenylboronic acid

2931900090

1. Suzuki Cross-Coupling Synthesis Application: 2-Boronobenzoic acid (CAS: 149105-19-1) is a common bifunctional boronic acid coupling reagent. It can efficiently participate in Suzuki-Miyaura cross-coupling reactions, introducing both carboxyl and aromatic structures into target molecules. The dual active functional groups greatly enrich the diversity of synthetic routes and are widely used in the construction of complex aromatic carboxylic acid compounds. 2. Coordination Chemistry & Catalysis Application: This product has unique bidentate coordination performance, which can form stable complex structures with metal ions, nitrogen, oxygen and silicon-containing compounds. It is commonly used as an organic ligand and chelating reagent in the preparation of metal-organic framework materials (MOFs) and homogeneous catalytic systems, effectively improving catalytic stability and reaction selectivity. 3. Pharmaceutical Intermediate Synthesis Application: 2-Boronobenzoic acid (CAS: 149105-19-1) serves as an important precursor for the synthesis of boron-containing drug intermediates and bioactive small molecules. The ortho-carboxy boronic acid structure can effectively regulate the molecular polarity and biological activity, and is widely applied in the research and development of anti-inflammatory, antibacterial and targeted therapeutic drug intermediates. 4. Fine Chemical Derivatization Application: It is suitable for customized synthesis of high-value functional fine chemicals and organic intermediates. Through carboxyl esterification, amination and boronic acid coupling derivatization reactions, a variety of high-purity functional aromatic derivatives can be prepared, meeting the refined production needs of modern fine chemical industry and material chemistry research.

≥98%

C7H7BO4

165.94

2 years under proper storage

White crystalline powder

Fine Chemical Grade, Pharmaceutical Intermediate Grade, Synthetic Reagent Grade

1.40±0.1 g/cm3 (Predicted)

138-141 °C

412.3±55.0 °C (Predicted)