2-Tolylboronic acid

2-Tolylboronic acid (CAS 16419-60-6) is a conventional high-purity aromatic organoboron fine chemical. This compound consists of a methyl-substituted benzene ring skeleton with active boronic acid functional groups, featuring mild moisture sensitivity, stable chemical properties and slight solubility in water and conventional organic solvents. The ortho-methyl substitution structure provides unique steric hindrance effects, effectively improving reaction specificity and reducing by-product generation in cross-coupling reactions. 2-Tolylboronic acid (CAS 16419-60-6) serves as a universal aromatic building block, widely applied in organic synthetic chemistry, pharmaceutical intermediate manufacturing and fine chemical industrial derivatization.

1. Suzuki-Miyaura Cross-Coupling Reaction Synthesis: 2-Tolylboronic acid (CAS 16419-60-6) is a core universal monomer for palladium-catalyzed Suzuki cross-coupling reactions. Its stable ortho-methylphenyl structure ensures high reaction activity and selectivity, and is widely used for industrial synthesis of methyl-substituted biaryl compounds and high-purity aromatic intermediates in fine chemical production. 2. Pharmaceutical Intermediate Customized Production: 2-Tolylboronic acid (CAS 16419-60-6) is a basic modular intermediate for new drug research and development. It can be used for the synthesis of enzyme inhibitor intermediates and anti-tumor small-molecule drug precursors, supporting structural optimization and customized synthesis of targeted pharmaceutical compounds. 3. Catalytic Ligand and Reagent Preparation: 2-Tolylboronic acid (CAS 16419-60-6) acts as a key raw material for preparing chiral phosphorus ligands and catalytic additives. It is applicable to asymmetric catalytic reactions and ligand-free copper-catalyzed coupling systems, improving catalytic efficiency and reaction stereoselectivity in organic industrial catalysis. 4. Laboratory Organic Synthesis Research: 2-Tolylboronic acid (CAS 16419-60-6) is a standard laboratory synthetic reagent with stable batch quality. It is commonly used for organic reaction mechanism verification, synthetic route exploration and new aromatic compound development in scientific research and chemical R&D projects.

99%

C7H9BO2

135.96

2 years under proper storage

Beige crystalline powder

Laboratory Grade, Industrial Grade, Pharmaceutical Grade

1.10±0.1 g/cm3

162-164°C

283.4±33.0°C at 760 mmHg