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2-Hydroxymethylphenylboronic acid

CAT: 1139-87199-14-2-01Size: 1 EachDry Ice: NoHazardous: No
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Description
2-Hydroxymethylphenylboronic acid (CAS 87199-14-2) is a high-purity hydroxyl-functionalized aromatic boronic acid fine chemical. It features a benzene ring skeleton grafted with hydroxymethyl and boronic acid dual active functional groups, presenting mild moisture sensitivity, stable chemical properties and excellent solubility in polar organic solvents. The dual reactive groups endow the compound with efficient cross-coupling activity and flexible molecular derivatization performance. 2-Hydroxymethylphenylboronic acid (CAS 87199-14-2) serves as a core hydroxyl-containing aromatic synthetic building block, widely applied in cross-coupling reaction synthesis, pharmaceutical intermediate customization and functional fine chemical modification in industrial production and laboratory scientific research.
Applications
1. Hydroxyl-Functionalized Suzuki Cross-Coupling Synthesis: 2-Hydroxymethylphenylboronic acid (CAS 87199-14-2) is a key reactive monomer for palladium-catalyzed Suzuki-Miyaura cross-coupling reactions. The unique hydroxymethyl-substituted benzene structure improves reaction diversity and product functionalization, which is widely used for synthesizing high-value hydroxyl biaryl fine chemical intermediates. 2. Functional Pharmaceutical Intermediate Manufacturing: 2-Hydroxymethylphenylboronic acid (CAS 87199-14-2) is an important modular intermediate for new drug R&D. The active hydroxyl and boronic acid groups can support multi-step molecular modification, optimizing drug molecular solubility and biological activity, and meeting the customized synthesis needs of anti-inflammatory and targeted therapeutic drug intermediates. 3. High-End Functional Fine Chemical Derivatization: 2-Hydroxymethylphenylboronic acid (CAS 87199-14-2) acts as a critical precursor for hydroxyl-functionalized fine chemicals. It can undergo esterification, substitution and cyclization reactions through dual active sites, realizing structural functional upgrading of aromatic fine chemical products for industrial batch production. 4. Laboratory Organic Synthesis Research: 2-Hydroxymethylphenylboronic acid (CAS 87199-14-2) is a standard high-purity laboratory organic synthesis reagent. With stable batch purity and controllable dual-group reaction characteristics, it is widely used for reaction mechanism verification and process optimization of hydroxymethyl-substituted phenylboronic acid compounds.
Purity
99%
Molecular Formula
C7H9BO3
Molecular Weight
151.96
Shelf Life
2 years under proper storage
Appearance
White to off-white crystalline powder
Grade
Laboratory Grade, Industrial Grade
Density
1.28±0.1 g/cm3
Melting Point
108-112°C
Boiling Point
344.6±52.0°C at 760 mmHg

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