NSC 694623

CAT: 0804-HY-147290-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-147290-01Size:5 mg
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Description
NSC 694623 is a potent histone acetyltransferase (HAT) inhibitor with an IC50 value of 15.9 μM for recombinant HAT p300/CBP-associated factor (PCAF) . NSC 694623 has antiproliferative activity against certain cancer cells. NSC 694623 can be used for researching anticancer[1].
CAS Number
[907957-34-0]
UNSPSC
12352005
Target
Histone Acetyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/nsc-694623.html
Purity
99.53
Solubility
DMSO : 125 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C1N(C2=CC=C(CCCC)C=C2)SC3=NC=CC=C31
Molecular Formula
C16H16N2OS
Molecular Weight
284.38
References & Citations
[1]Furdas SD, et al. Synthesis and biological testing of novel pyridoisothiazolones as histone acetyltransferase inhibitors. Bioorg Med Chem. 2011 Jun 15;19 (12) :3678-89.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
GCN5/PCAF

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