2,3,4-Trifluorophenylboronic acid

2,3,4-Trifluorophenylboronic acid (CAS 226396-32-3) is a high-purity trifluorinated aromatic boronic acid fine chemical. This compound features a benzene ring skeleton with three fluorine atoms substituted at the 2, 3 and 4 positions, equipped with active boronic acid functional groups with excellent cross-coupling reaction activity. It has strict moisture-sensitive characteristics and requires low-temperature inert sealed storage to maintain stable molecular structure and chemical activity. The continuous trifluorine substitution structure endows the product with superior lipophilicity, chemical stability and unique electronic effects, which cannot be replaced by ordinary fluorinated boronic acid products. 2,3,4-Trifluorophenylboronic acid (CAS 226396-32-3) is widely used in organic catalytic synthesis, high-end fluorinated pharmaceutical intermediate preparation and functional fine chemical derivatization, serving as a core synthetic building block for laboratory research and industrial mass production.

1. Suzuki-Miyaura Cross-Coupling Reaction Synthesis: 2,3,4-Trifluorophenylboronic acid (CAS 226396-32-3) is a high-efficiency fluorinated monomer for palladium-catalyzed cross-coupling reactions. Its continuous trifluorine substituted structure optimizes molecular electronic distribution and steric hindrance, significantly improving the synthesis efficiency and product purity of multi-fluorinated biaryl compounds, and is widely used in industrial batch synthesis of high-purity fluorinated fine chemicals. 2. Multi-Fluorinated Pharmaceutical Intermediate Manufacturing: 2,3,4-Trifluorophenylboronic acid (CAS 226396-32-3) is a key customized intermediate for new fluorinated drug development. The continuous trifluorine functional group greatly enhances the metabolic stability, lipophilicity and biological activity of drug molecules, and is mainly used for structural modification and synthesis of high-value anti-tumor, antiviral and anti-inflammatory small-molecule pharmaceutical intermediates. 3. Functional Fluorinated Fine Chemical Derivatization: 2,3,4-Trifluorophenylboronic acid (CAS 226396-32-3) acts as an important industrial precursor for multi-fluorinated aromatic fine chemicals. The active boronic acid group supports multi-step substitution, condensation and cyclization reactions, enabling the preparation of high-performance fluorinated functional additives and new material monomers for pharmaceutical, electronic material and fine chemical industries. 4. Fluorinated Organic Chemistry Research: 2,3,4-Trifluorophenylboronic acid (CAS 226396-32-3) is a standard high-purity experimental reagent for fluorinated organic catalytic research. With stable batch quality and unique continuous trifluorine substitution characteristics, it is commonly used to verify fluorinated reaction mechanisms and develop new synthetic routes of multi-fluorinated aromatic compounds.

≥98%

C6H4BF3O2

175.90

2 years under proper storage

White crystalline powder

Laboratory Grade, Industrial Grade, Pharmaceutical Grade

1.43±0.1 g/cm3

229-235°C

292.4±50.0°C at 760 mmHg