2,4,5-Trifluorophenylboronic acid

2,4,5-Trifluorophenylboronic acid (CAS 247564-72-3) is a high-purity multi-fluorinated aromatic boronic acid fine chemical. This compound consists of a benzene ring skeleton with three fluorine substituents at the 2, 4, and 5 positions, equipped with reactive boronic acid functional groups, presenting typical moisture-sensitive chemical properties. It maintains stable molecular structure and excellent cross-coupling reaction activity under sealed, dry and room-temperature storage conditions, and is soluble in common polar organic solvents used in organic synthesis. The unique asymmetric trifluoro-substituted structure endows the product with superior chemical stability, adjustable molecular polarity and high reaction selectivity, making it a high-value customized fluorinated aromatic building block. 2,4,5-Trifluorophenylboronic acid (CAS 247564-72-3) is widely utilized in organic cross-coupling synthesis, fluorinated pharmaceutical intermediate development and high-end fine chemical derivatization for laboratory research and industrial mass production.

1. Suzuki-Miyaura Cross-Coupling Reaction Synthesis: 2,4,5-Trifluorophenylboronic acid (CAS 247564-72-3) serves as a high-activity monomer for palladium-catalyzed cross-coupling reactions. Its special 2,4,5-trifluorinated benzene structure optimizes molecular electronic distribution and steric hindrance, effectively improving the synthesis yield and product purity of asymmetric trifluorinated biaryl compounds for industrial batch production of high-end fluorinated fine chemical products. 2. Fluorinated Pharmaceutical Intermediate Manufacturing: 2,4,5-Trifluorophenylboronic acid (CAS 247564-72-3) is a core modular intermediate for new drug research and development. The asymmetric trifluoro functional groups significantly enhance the lipophilicity, metabolic stability and biological activity of drug molecules, supporting structural modification and customized synthesis of antiviral, anti-tumor and anti-inflammatory small-molecule pharmaceutical intermediates. 3. High-End Fluorinated Fine Chemical Derivatization: 2,4,5-Trifluorophenylboronic acid (CAS 247564-72-3) acts as an essential industrial precursor for diversified trifluorinated aromatic fine chemicals. The active boronic acid functional group supports multi-step substitution, condensation and cyclization reactions, enabling the preparation of high-performance fluorinated functional materials and special chemical additives for pharmaceutical and new material industries. 4. Organic Catalytic Mechanism Research: 2,4,5-Trifluorophenylboronic acid (CAS 247564-72-3) is a standard high-purity experimental reagent for organic chemistry and catalytic research. With stable batch quality and unique asymmetric trifluorinated structural characteristics, it is widely used for verifying fluorinated organic reaction mechanisms and developing new synthetic routes of fluorine-containing fine chemicals in scientific research projects.

99%

C6H4BF3O2

175.90

2 years under proper storage

White to off-white crystalline powder

Laboratory Grade, Industrial Grade, Pharmaceutical Grade

1.44±0.1 g/cm3

100°C