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2,3-Dichlorophenylboronic acid

CAT: 1139-151169-74-3Size: 1 EachDry Ice: NoHazardous: No
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Description
2,3-Dichlorophenylboronic acid (CAS 151169-74-3) is a high-purity ortho-dichlorinated aromatic boronic acid fine chemical. This compound features a benzene ring skeleton modified with dichloro substituents at the 2 and 3 positions and active boronic acid functional groups, presenting strict moisture-sensitive and thermal decomposition characteristics. It requires ultra-low temperature inert sealed storage to maintain stable molecular structure and excellent cross-coupling reaction activity, and is soluble in conventional polar organic solvents such as methanol. The adjacent dichloro substitution structure endows the product with unique molecular polarity, high reaction selectivity and stable chemical properties, making it a high-value synthetic intermediate different from ordinary phenylboronic acid derivatives. 2,3-Dichlorophenylboronic acid (CAS 151169-74-3) serves as a core dichlorinated aromatic building block, widely applied in organic cross-coupling synthesis, pharmaceutical intermediate development and fine chemical derivatization for laboratory research and industrial fine chemical mass production.
Applications
1. Suzuki Cross-Coupling Reaction Synthesis: 2,3-Dichlorophenylboronic acid (CAS 151169-74-3) is a high-activity monomer for palladium-catalyzed Suzuki-Miyaura cross-coupling reactions. Its unique 2,3-dichloro disubstituted benzene structure optimizes molecular electronic distribution and steric stability, effectively improving the synthesis efficiency and product purity of ortho-dichlorinated biaryl compounds for industrial batch synthesis of high-value chlorinated aromatic fine chemicals. 2. Pharmaceutical Intermediate Customized Synthesis: 2,3-Dichlorophenylboronic acid (CAS 151169-74-3) is a critical modular intermediate for new drug research and development. The adjacent dichloro functional groups enhance the molecular metabolic stability and biological activity, supporting structural modification and customized synthesis of kinase inhibitors, anti-inflammatory analgesics and targeted therapeutic small-molecule drug intermediates. 3. Chlorinated Fine Chemical Derivatization: 2,3-Dichlorophenylboronic acid (CAS 151169-74-3) acts as an essential industrial precursor for diversified dichlorinated aromatic fine chemicals. The active boronic acid functional group supports multi-step substitution, condensation and cyclization reactions, enabling the preparation of high-end chlorinated functional materials and special chemical additives for pharmaceutical and fine chemical industries. 4. Organic Synthetic Mechanism Research: 2,3-Dichlorophenylboronic acid (CAS 151169-74-3) is a standard high-purity experimental reagent for organic chemistry research. With stable batch quality and unique ortho-dichlorinated structural characteristics, it is widely used for organic reaction mechanism verification and development of new chlorinated aromatic compound synthetic routes in scientific research projects.
Purity
99%
Molecular Formula
C6H5BCl2O2
Molecular Weight
190.82
Shelf Life
2 years under proper storage
Appearance
White crystalline powder
Grade
Laboratory Grade, Industrial Grade, Pharmaceutical Grade
Density
1.47±0.1 g/cm3
Melting Point
125°C (dec.)
Boiling Point
349.8±52.0°C at 760 mmHg