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2,4-Dichlorophenylboronic acid

CAT: 1139-68716-47-2-01Size: 1 EachDry Ice: NoHazardous: No
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Description
2,4-Dichlorophenylboronic acid (CAS 68716-47-2) is a high-purity dichloro-substituted aromatic boronic acid fine chemical. This compound features a stable benzene ring skeleton with 2,4-dichloro substituents and active boronic acid functional groups, presenting typical moisture-sensitive chemical properties. It maintains stable molecular structure and excellent cross-coupling reaction activity under low-temperature inert sealed storage, and has good solubility in polar organic solvents such as methanol. The dual chlorine substitution structure endows the product with unique electronic effects, excellent reaction selectivity and molecular modifiability in organic synthesis. 2,4-Dichlorophenylboronic acid (CAS 68716-47-2) serves as a core dichlorinated aromatic building block, widely applied in pharmaceutical intermediate synthesis, organic cross-coupling reactions and high-value fine chemical derivatization in laboratory research and industrial production.
Applications
1. Dichlorinated Aromatic Cross-Coupling Synthesis: 2,4-Dichlorophenylboronic acid (CAS 68716-47-2) is a core reaction monomer for palladium-catalyzed Suzuki-Miyaura cross-coupling reactions. Its unique 2,4-dichloro substituted benzene structure optimizes reaction stability and selectivity, effectively reducing by-product generation, and is widely used for industrial batch synthesis of high-purity dichlorinated biaryl fine chemical intermediates. 2. Pharmaceutical Intermediate Customized Manufacturing: 2,4-Dichlorophenylboronic acid (CAS 68716-47-2) is an essential modular intermediate for new drug development. The dichloro aromatic structure can adjust drug molecular lipophilicity and biological activity, supporting structural optimization and customized synthesis of lactate dehydrogenase inhibitors, MK2 inhibitors and other bioactive small-molecule pharmaceutical intermediates. 3. Fine Chemical Derivatization Production: 2,4-Dichlorophenylboronic acid (CAS 68716-47-2) acts as a critical industrial precursor for high-value dichlorinated aromatic derivatives. The active boronic acid functional group supports multi-step substitution, hydroxylation and condensation reactions, enabling the preparation of diversified functional fine chemicals for biochemical reagents and high-end chemical additive production. 4. Laboratory Organic Synthesis Research: 2,4-Dichlorophenylboronic acid (CAS 68716-47-2) is a standard high-purity laboratory synthetic reagent. With stable batch quality and unique dichloro-substituted aromatic reaction characteristics, it is widely used for organic reaction mechanism verification, synthetic route optimization and new bioactive compound development in scientific research projects.
Purity
99%
Molecular Formula
C6H5BCl2O2
Molecular Weight
190.82
Shelf Life
2 years under proper storage
Appearance
White to off-white powder
Grade
Laboratory Grade, Industrial Grade, Pharmaceutical Grade
Density
1.47±0.1 g/cm3
Melting Point
246-249°C
Boiling Point
331.3±52.0°C at 760 mmHg