Allylboronic acid pinacol ester

Allylboronic acid pinacol ester (CAS:72824-04-5) is a high-purity aliphatic alkenyl boronic acid pinacol ester compound. It features a stable pinacol boronate structure and active allyl unsaturated double bond, with low density, good fluidity and excellent solubility in conventional organic solvents. Compared with ordinary boronic acids, it has significantly improved hydrolysis resistance and chemical stability, and is not easy to decompose under mild reaction conditions. It is a classic and high-efficiency allyl boron building block, widely used in organic synthesis, pharmaceutical intermediate derivation and fine chemical customization.

2-Allyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane, 4,4,5,5-Tetramethyl-2- (2-propen-1-yl) -1,3,2-dioxaborolane, Allylboronic acid pinacolate

Not available

1. Suzuki Cross-Coupling Reactions: Allylboronic acid pinacol ester (72824-04-5) is a core aliphatic boron coupling reagent for Suzuki cross-coupling reactions. The stable pinacol ester structure effectively inhibits boron group hydrolysis during the reaction, while the active allyl group efficiently participates in molecular splicing. It can stably introduce allyl unsaturated fragments into aromatic and heterocyclic compounds, with high reaction yield and low side reactions, suitable for laboratory synthesis and industrial scale-up production. 2. Allyl-Containing Pharmaceutical Intermediate Synthesis: This Allylboronic acid pinacol ester (CAS 72824-04-5) serves as a key synthetic intermediate for allyl-modified drug molecules. The allyl functional group can be used for subsequent cyclization, oxidation and addition derivatization, widely applied in the R&D of anti-tumor, anti-inflammatory and antiviral small-molecule drugs, providing unique unsaturated aliphatic structural units for innovative drug molecular design. 3. Organic Molecular Functional Modification: It is dedicated to directional structural modification of complex organic molecules. With dual active sites of carbon-carbon double bond and boronate group, it can realize stepwise functional grafting and structural optimization, supporting the customized synthesis of high-value fine chemical intermediates and bioactive molecular fragments. 4. Medicinal Chemistry and Material Research: Allylboronic acid pinacol ester (72824-04-5) is commonly used in compound library screening and synthetic process optimization in biomedical research. Its stable chemical properties reduce experimental errors, providing reliable raw material support for new drug development and organic functional material innovation.

≥98%

C9H17BO2

168.04

2 years under proper storage

Colorless transparent liquid

Fine Chemical Grade, Laboratory Grade, Synthetic Intermediate Grade

0.896±0.01 g/cm3 (25 °C, lit.)

Not available