Boric Acid, Pinacol Ester

Boric Acid, Pinacol Ester (CAS 25240-59-9) is a fundamental and highly stable organic boronic ester compound, commonly known as Pinacolboronic Acid (HOBpin) . It features a five-membered dioxaborolane ring structure with reactive hydroxyl groups, exhibiting better chemical stability and hydrolysis resistance than ordinary boronic acids. The product is white crystalline solid at room temperature, soluble in common organic solvents such as dichloromethane, chloroform, ether and ketones, slightly soluble in water. As a basic boron-containing building block, it is widely used in organic synthesis, cross-coupling reactions and pharmaceutical intermediate derivatization.

2-Hydroxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane, Pinacolboronic acid, HOBpin, Pinacol boric acid ester

2931900090

1. Universal Boron Reagent for Suzuki Coupling Reactions: Boric Acid, Pinacol Ester (CAS 25240-59-9) serves as a core foundational boron reagent for Suzuki-Miyaura cross-coupling reactions. It can react with various halogenated hydrocarbons to construct carbon-carbon bonds, featuring mild reaction conditions, high conversion rate and low side reactions. Its excellent stability effectively avoids the decomposition problems of traditional boronic acid reagents during synthesis and purification. 2. Precursor for Boronic Ester Intermediate Synthesis: Boric Acid, Pinacol Ester (CAS 25240-59-9) is a key precursor for the preparation of various functional pinacol boronic ester derivatives. Through efficient functional group substitution and condensation reactions, it can synthesize aryl boronic esters, alkyl boronic esters and heterocyclic boronic ester intermediates, covering most fine chemical and pharmaceutical synthetic needs. 3. Pharmaceutical and Fine Chemical Intermediate Derivatization: Boric Acid, Pinacol Ester (CAS 25240-59-9) is widely applied in the structural modification of drug molecules and fine chemicals. It is commonly used for boron functionalization of complex organic skeletons, supporting the synthesis of anti-tumor, anti-inflammatory and antiviral drug intermediates, and optimizing product molecular activity and stability. 4. Laboratory Organic Synthetic Research: Boric Acid, Pinacol Ester (CAS 25240-59-9) is an essential standard reagent for organic chemistry laboratories. It is frequently used in the research of new catalytic systems, synthetic process optimization and novel boron-containing compound development, providing reliable raw material support for academic experiments and industrial process exploration.

≥97%

C6H13BO3

143.98

2 years under proper storage

White crystalline solid

Laboratory Grade, Fine Chemical Grade, Synthetic Intermediate Grade

1.04±0.1 g/cm3 (Predicted)

38-42 °C

178.6±23.0 °C at 760 mmHg