Products for Research Use Only
RegisterLogin

Pempidine (hydrochloride)

CAT: 0804-HY-B1382ASize: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-B1382ASize:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Pempidine (1,2,2,6,6-Pentamethylpiperidine) hydrochloride is an orally active ganglionic blocking agent used in the treatment of hypertension. Pempidine hydrochloride blocks the effects of intravenously administered addictive drugs and peripheral vagal nerve stimulation on blood pressure, and reduces the output of acetylcholine[1][2][3].
CAS Number
6152-95-0
Product Name Alternative
1,2,2,6,6-Pentamethylpiperidine (hydrochloride)
UNSPSC
12352005
Target
NAChR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/pempidine-hydrochloride.html
Smiles
CC1(C)CCCC(C)(C)N1C.Cl
Molecular Formula
C10H22ClN
Molecular Weight
191.74
References & Citations
[1]Martin TJ, et al. Pharmacological evaluation of the antagonism of nicotine's central effects by mecamylamine and pempidine. J Pharmacol Exp Ther. 1990 Jul;254 (1) :45-51.|[2]L. BRETHERICK, Congeners of Pempidine with High Ganglion-blocking Activity. Nature, 1959, 184: 1707-1709) |[3]Haikala, H., & Ahtee, L. (1988) . Antagonism of the nicotine-induced changes of the striatal dopamine metabolism in mice by mecamylamine and pempidine. Naunyn-Schmiedeberg's archives of pharmacology, 338 (2), 169–173.|[4]MUGGLETON, D. F., & READING, H. W. (1959) . Absorption, metabolism and elimination of pempidine in the rat. British journal of pharmacology and chemotherapy, 14 (2), 202–208.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-B1382-01Pempidine
HY-B0500BAlverine (hydrochloride)
HY-N14912β-Prumycin hydrochloride
HY-N0300A-01Tetrahydropalmatine (hydrochloride)
HY-172541LN6023 (hydrochloride)
HY-172070-01Metaescaline (hydrochloride)
HY-170052-01α-Isopropylaminohexanophenone (hydrochloride)
HY-168824-01Cypenamine (hydrochloride)
HY-161794A-01SP3N (hydrochloride)
HY-157255α-Dimethylaminopentiophenone (hydrochloride)

Alternative Products

CatalogName
MBS3605977-01Pempidine
MBS5811546Pempidine HCl
MBS5811672Pempidine tartrate
414835Pempidine Free Base
300563Ligustrazine Hydrochloride (Chuanxiongzine hydrochloride)
D3190-91GDeoxynojirimycin Hydrochloride (DNJ Hydrochloride)
OR1043462-01Hydrochloride
MBS6103001-01O-Cyclopropylmethyl-hydroxylamine, Hydrochloride (Cyclopropylmethoxyamine, Hydrochloride, Cyclopropylmethoxylamine, Hydrochloride)
C7050-01Cysteamine hydrochloride; 2-AminoeThanethiol Hydrochloride; 2-Aminoethane-1-Thiol Hydrochloride; Mercaptamine Hydrochloride
P9050-45Propargylamine, Hydrochloride (2-Propynylamine, Hydrochloride)

Popular Products