Products for Research Use Only

Sgo2 Polyclonal Antibody

CAT: 1027-RA29779-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:1027-RA29779-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Function:During meiosis, protects centromeric cohesion complexes until metaphase II/anaphase II transition, preventing premature release of meiosis-specific REC8 cohesin complexes from anaphase I centromeres. Is thus essential for an accurate gametogenesis (By similarity) . May act by targeting PPP2CA to centromeres, thus leading to cohesin dephosphorylation., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., sequence caution:Contaminating sequence. Potential poly-A sequence., similarity:Belongs to the shugoshin family., subcellular location:In Hela cells, localizes at centromeres throughout prophase until metaphase and disappears at anaphase., subunit:Directly interacts with PPP2CA.
Product Name Alternative
SGOL2; Shugoshin-like 2; Shugoshin-2; Sgo2; Tripin
Gene ID
151246
Swiss Prot
Q562F6
Cross Reactivity
Human; Rat; Mouse
Clonality
Polyclonal
Source
Rabbit
Applications
IHC-p; IF (paraffin section) ; ELISA
Dilution
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage Conditions
-20°C/1 year