Products for Research Use Only

Sgo2 Polyclonal Antibody

CAT: 0965-JOT-AP08267-01Size: 20 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0965-JOT-AP08267-01Size:20 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Cooperates with PPP2CA to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I. Has a crucial role in protecting REC8 at centromeres from cleavage by separase. During meiosis, protects centromeric cohesion complexes until metaphase II/anaphase II transition, preventing premature release of meiosis-specific REC8 cohesin complexes from anaphase I centromeres. Is thus essential for an accurate gametogenesis. May act by targeting PPP2CA to centromeres, thus leading to cohesin dephosphorylation (By similarity). Essential for recruiting KIF2C to the inner centromere and for correcting defective kinetochore attachments.
CAS Number
9007-83-4
Synonyms
SGOL2; Shugoshin-like 2; Shugoshin-2; Sgo2; Tripin
Host
Rabbit
Reactivity
Human
Immunogen
The antiserum was produced against synthesized peptide derived from human SGOL2. AA range:681-730
Clonality
Polyclonal
Applications
IHC-p, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
144739
Antibody Type
Primary antibody
Isotype
IgG

Popular Products