NARF Polyclonal Antibody

• Background :

  Nuclear prelamin A recognition factor (NARF) Homo sapiens Several proteins have been found to be prenylated and methylated at their carboxyl-terminal ends. Prenylation was initially believed to be important only for membrane attachment. However, another role for prenylation appears to be its importance in protein-protein interactions. The only nuclear proteins known to be prenylated in mammalian cells are prelamin A- and B-type lamins. Prelamin A is farnesylated and carboxymethylated on the cysteine residue of a carboxyl-terminal CaaX motif. This post-translationally modified cysteine residue is removed from prelamin A when it is endoproteolytically processed into mature lamin A. The protein encoded by this gene binds to the prenylated prelamin A carboxyl-terminal tail domain. It may be a component of a prelamin A endoprotease complex. The encoded protein is located in the nucleus, where it partially colocalizes with the nuclear lamina. It

• Product Name Alternative :

  NARF; Nuclear prelamin A recognition factor; Iron-only hydrogenase-like protein 2; IOP2

• Gene ID :

  26502

• Swiss Prot :

  Q9UHQ1

• Cross Reactivity :

  Human; Rat; Mouse

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA

• Dilution :

  Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

• Buffer :

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Molecular Weight :

  51

• Storage Conditions :

  -20°C/1 year

• Protein Weight :

  51