AG 99

CAT: 0804-HY-100962ASize: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-100962ASize:1 Each
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Description
AG 99 (Tyrphostin 46), a tyrphostin derivative, is a tyrosine kinase inhibitor that increases sister chromatid exchange frequency in transformed CHO-K1 and primary CHE cells. AG 99 is promising for research of proliferative diseases[1].
CAS Number
[118409-59-9]
Product Name Alternative
Tyrphostin 46; Tyrphostin AG 99
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Tyrosinase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ag-99.html
Smiles
O=C(/C(C#N)=C/C1=CC=C(C(O)=C1)O)N
Molecular Formula
C10H8N2O3
Molecular Weight
204.18
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Bassi L, et al. Clastogenic effects of two tyrosine kinase inhibitors, tyrphostin 23 and tyrphostin 46, on a transformed (CHO-K1) and on a primary embryonic chinese hamster cell line (CHE) . Mutagenesis. 2000 Jul;15 (4) :341-7.|[2]Hubert EM, et al. Inhibition of volume-stimulated taurine efflux and tyrosine kinase activity in the skate red blood cell. Pflugers Arch. 2000 May;440 (1) :132-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched

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