AG 99

• UNSPSC Description:

  AG 99 (Tyrphostin 46), a tyrphostin derivative, is a tyrosine kinase inhibitor that increases sister chromatid exchange frequency in transformed CHO-K1 and primary CHE cells. AG 99 is promising for research of proliferative diseases[1].

• Target Antigen:

  Tyrosinase

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/ag-99.html

• Smiles:

  O=C(/C(C#N)=C/C1=CC=C(C(O)=C1)O)N

• Molecular Weight:

  204.18

• References & Citations:

  [1]Bassi L, et al. Clastogenic effects of two tyrosine kinase inhibitors, tyrphostin 23 and tyrphostin 46, on a transformed (CHO-K1) and on a primary embryonic chinese hamster cell line (CHE). Mutagenesis. 2000 Jul;15(4):341-7.|[2]Hubert EM, et al. Inhibition of volume-stimulated taurine efflux and tyrosine kinase activity in the skate red blood cell. Pflugers Arch. 2000 May;440(1):132-9.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  Launched

• CAS Number:

  118409-59-9