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CD158z Antibody

CAT: 1071-OM636610-01Size: 100 µLDry Ice: NoHazardous: No
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CAT#:1071-OM636610-01Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13. 4 within the 1 Mb leukocyte receptor complex (LRC) . The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2) . The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human KIR3DL3. AA range:231-280
Antibody Type
Primary Antibodies
Product Name Synonym
KIR3DL3 antibody; CD158Z antibody; KIR3DL7 antibody; KIRC1 antibody; Killer cell immunoglobulin-like receptor 3DL3 antibody; CD158 antigen-like family member Z antibody; Killer cell inhibitory receptor 1 antibody; CD158z antibody

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