CD148 Antibody

CAT: 1071-OM636659-01Size: 100 µLDry Ice: NoHazardous: No
CAT#:1071-OM636659-01Size:100 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes, including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region containing five fibronectin type III repeats, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. This protein is present in all hematopoietic lineages, and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 and Linker for Activation of T Cells. This protein can also dephosphorylate the PDGF beta receptor, and may be involved in UV-induced signal transduction. Multiple transcript variants encoding different isoforms
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human PTPRJ. AA range:861-910
Antibody Type
Primary Antibodies
Product Name Synonym
PTPRJ antibody; DEP1 antibody; Receptor-type tyrosine-protein phosphatase eta antibody; Protein-tyrosine phosphatase eta antibody; R-PTP-eta antibody; Density-enhanced phosphatase 1 antibody; DEP-1 antibody; HPTP eta antibody; Protein-tyrosine phosphatase receptor type J antibody; R-PTP-J antibody; CD148 antibody

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