CD148 Antibody

• Description :

  The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes, including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region containing five fibronectin type III repeats, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. This protein is present in all hematopoietic lineages, and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 and Linker for Activation of T Cells. This protein can also dephosphorylate the PDGF beta receptor, and may be involved in UV-induced signal transduction. Multiple transcript variants encoding different isoforms

• Immunogen :

  The antiserum was produced against synthesized peptide derived from the Internal region of human PTPRJ. AA range:861-910

• Antibody Type :

  Primary Antibodies

• Product Name Synonym :

  PTPRJ antibody; DEP1 antibody; Receptor-type tyrosine-protein phosphatase eta antibody; Protein-tyrosine phosphatase eta antibody; R-PTP-eta antibody; Density-enhanced phosphatase 1 antibody; DEP-1 antibody; HPTP eta antibody; Protein-tyrosine phosphatase receptor type J antibody; R-PTP-J antibody; CD148 antibody