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NCX1 Antibody

CAT: 1071-OM636535-01Size: 100 µLDry Ice: NoHazardous: No
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CAT#:1071-OM636535-01Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
In cardiac myocytes, Ca (2+) concentrations alternate between high levels during contraction and low levels during relaxation. The increase in Ca (2+) concentration during contraction is primarily due to release of Ca (2+) from intracellular stores. However, some Ca (2+) also enters the cell through the sarcolemma (plasma membrane) . During relaxation, Ca (2+) is sequestered within the intracellular stores. To prevent overloading of intracellular stores, the Ca (2+) that entered across the sarcolemma must be extruded from the cell. The Na (+) -Ca (2+) exchanger is the primary mechanism by which the Ca (2+) is extruded from the cell during relaxation. In the heart, the exchanger may play a key role in digitalis action. The exchanger is the dominant mechanism in returning the cardiac myocyte to its resting state following excitation.
Immunogen
Synthesized peptide derived from NCX1 . at AA range: 270-350
Antibody Type
Primary Antibodies
Product Name Synonym
SLC8A1 antibody; CNC antibody; NCX1 antibody; Sodium/calcium exchanger 1 antibody; Na (+) /Ca (2+) -exchange protein 1 antibody

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