Products for Research Use Only

Sck Antibody

CAT: 1071-OM636004-01Size: 100 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:1071-OM636004-01Size:100 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Domain:The PID domain mediates binding to the TrkA receptor. Signaling adapter that couples activated growth factor receptors to signaling pathway in neurons. Involved in the signal transduction pathways of neurotrophin-activated Trk receptors in cortical neurons. miscellaneous:PubMed:15057824 has shown that SHC2 is poorly phosphorylated by the Trk receptors, in opposite to PubMed:12006576. PTM:Phosphorylated on tyrosines by the Trk receptors. Contains 1 PID domain. Contains 1 SH2 domain. subunit:Interacts with the Trk receptors in a phosphotyrosine-dependent manner and MEGF12. Once activated, binds to GRB2. tissue specificity:Expressed in brain. Expressed at high level in the hypothalamus and at low level in the caudate nucleus.
Immunogen
The antiserum was produced against synthesized peptide derived from human SHC2. AA range:261-310
Antibody Type
Primary Antibodies
Product Name Synonym
SHC2 antibody; SCK antibody; SHCB antibody; SHC-transforming protein 2 antibody; Protein Sck antibody; SHC-transforming protein B antibody; Src homology 2 domain-containing-transforming protein C2 antibody; SH2 domain protein C2 antibody