PHM-27 (Human)

• Description:

  PHM-27 (Human) Catalog number: MDP0561 CAS Number: 135842-15-8 Sequence: His-Ala-Asp-Gly-Val-Phe-Thr-Ser-Asp-Phe-Ser-Lys-Leu-Leu-Gly-Gln-Leu-Ser-Ala-Lys-Lys-Tyr-Leu-Glu-Ser-Leu-Met-NH2 Amount: 500 ug Molecular Weight: 2985.2 g/mol Supplied as: Powder Applications: molecular tool for various biochemical applications Storage: -20 °C WARNING: For in vitro Research Use Only. NOT for use on humans or animals. Grade: Biotechnology grade. All products are highly pure. References: 1: Yamagami T, Ohsawa K, Nishizawa M, Inoue C, Gotoh E, Yanaihara N, Yamamoto H, Okamoto H. Complete nucleotide sequence of human vasoactive intestinal peptide/PHM-27 gene and its inducible promoter Ann N Y Acad Sci. 1988;527:87-102. 2: Hayakawa Y, Obata K, Itoh N, Yanaihara N, Okamoto H. Cyclic AMP regulation of pro-vasoactive intestinal polypeptide/PHM-27 synthesis in human neuroblastoma cells J Biol Chem. 1984 Jul 25;259(14):9207-11. 3: Itoh N, Obata K, Yanaihara N, Okamoto H. Human preprovasoactive intestinal polypeptide contains a novel PHI-27-like peptide, PHM-27 Nature. 1983 Aug 11-17;304(5926):547-9. 4: Ma JN, Currier EA, Essex A, Feddock M, Spalding TA, Nash NR, Brann MR, Burstein ES. Discovery of novel peptide/receptor interactions: identification of PHM-27 as a potent agonist of the human calcitonin receptor Biochem Pharmacol. 2004 Apr 1;67(7):1279-84. 5: Xiao P, Guo S, Wen X, He QT, Lin H, Huang SM, Gou L, Zhang C, Yang Z, Zhong YN, Yang CC, Li Y, Gong Z, Tao XN, Yang ZS, Lu Y, Li SL, He JY, Wang C, Zhang L, Kong L, Sun JP, Yu X. Tethered peptide activation mechanism of the adhesion GPCRs ADGRG2 and ADGRG4 Nature. 2022 Apr;604(7907):771-778. 6: Hoshino M, Yanaihara C, Ogino K, Iguchi K, Sato H, Suzuki T, Yanaihara N. Production of VIP- and PHM (human PHI)-related peptides in human neuroblastoma cells Peptides. 1984 Mar-Apr;5(2):155-60. 7: Bodner M, Fridkin M, Gozes I. Coding sequences for vasoactive intestinal peptide and PHM-27 peptide are located on two adjacent exons in the human genome Proc Natl Acad Sci U S A. 1985 Jun;82(11):3548-51. 8: Ohsawa K, Hayakawa Y, Nishizawa M, Yamagami T, Yamamoto H, Yanaihara N, Okamoto H. Synergistic stimulation of VIP/PHM-27 gene expression by cyclic AMP and phorbol esters in human neuroblastoma cells Biochem Biophys Res Commun. 1985 Nov 15;132(3):885-91. 9: Kato I, Suzuki Y, Akabane A, Yonekura H, Tanaka O, Kondo H, Takasawa S, Yoshimoto T, Okamoto H. Transgenic mice overexpressing human vasoactive intestinal peptide (VIP) gene in pancreatic beta cells. Evidence for improved glucose tolerance and enhanced insulin secretion by VIP and PHM-27 in vivo J Biol Chem. 1994 Aug 19;269(33):21223-8. 10: Schulte-Bockholt A, Meier DA, Hopp K, Stadelmann A, Otterson MF, Telford GL, Koch TR. Gene expression and transcript size of the prepro-peptide VIP/PHM-27 in normal human tissue Neurosci Lett. 1993 Dec 24;164(1-2):101-4.
  Products Related to PHM-27 (Human) can be found at Peptides

• Short Description:

  Catalog Number: MDP0561 (500 ug)

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height:

  0.5